Title : FEV1 / FEV6 microspirometry – as a screening tool for chronic obstructive pulmonary disease.
Background: Various studies in India have found that the prevalence of undiagnosed COPD is between 4 to 18.2 %. The microspirometry, which is based on measurements FEV1 (forced expiratory volume in 1 second), FEV6 (forced expiratory volume in 6 seconds), and their ratio, has been found 'a reliable screening tool' in various studies, which can reduce underdiagnosis of COPD in primary care.
Aim: Validation of handheld FEV1/FEV6 micro spirometer in an Indian population.
Method: A pilot sample of 141 patients was taken for the study. Patients with respiratory symptoms and exposure to risk factors for COPD were subjected to pre-bronchodilator (BD) FEV1/FEV6 microspirometry and post-BD FEV1/FVC (Forced vital capacity) full spirometry. A pre-BD FEV1/FEV6 value < 0.88 as measured with the Piko-6 micro spirometer was compared with a post-BD FVC < 0.70 from diagnostic spirometry.
Result: The majority of our study participants (53.9%) were having COPD, while 46.1% didn't have the condition. For an FEV1/FEV6 ratio of 0.88, the sensitivity and specificity of the test are 84% and 51% respectively.
Conclusion: The situation of underdiagnosis of COPD could be improved through screening using portable/hand-held devices simpler than conventional spirometers in specific health care settings to reach a higher percentage of the at-risk population.