Exercise induced muscle carbohydrate oxidation and its mechanisms are the panacea for overconsumption of carbohydrate. To my knowledge, muscle contraction is the only mechanism for Glut-4 protein translocation from within the cell to the cell surface for glucose uptake. Add [....] » Read More
High intake of refined carbohydrates with low consumption of dietary fibres (DFs), particularly from vegetables and has increased the risk of CVD, diabetes and other illnesses. The prevalence of chronic diseases is increasingly skyrocketing with the number of diabetic individuals [....] » Read More
The study of the association between cancer and diabetes mellitus (DM) has been under investigation for decades. Particularly, in the field of neurology and neurosurgery, increasing attention has been paid to comorbid DM in cranial tumor patients, namely those afflicted with the [....] » Read More
The metabolic syndrome is a provocative clinical entity that is characterized by several cardiometabolic risk aspects including obesity, hypertension, and insulin resistance. This confluence is associated with an augmented peril of type 2 diabetes and cardiovascular disease. Diab [....] » Read More
Background Mucormycosis has been reported in several Indian states with the second wave of COVID-19 from January 2021 onwards. This prospective study was conducted with the objective of defining the contribution or association of various known and many suspected factors in the [....] » Read More
Points of Discussion: Prevalence of Diabetes, Effect of Diabetes on vascular dysfunction, Biomarkers targeting vascular dysfunction in diabetic condition, possible treatments. There are around 100 million people worldwide who have diabetes mellitus. 5% to 10% of people have type [....] » Read More
Introduction: Our previous study demonstrated that adipocyte MTP regulates intracellular lipolysis by inhibiting ATGL activity. Adipose-specific MTP knockout mice (A-Mttp-/-) had smaller adipocytes and showed increased thermogenesis, and gained less weight on an obesogenic diet. [....] » Read More
Given the role of insulin resistance in several types of cancer, we assumed that taking a diabetic diet that reduces insulin resistance may reduce the risk of breast cancer in women. Materials and Methods: In this literature review, a comprehensive electronic search of diff [....] » Read More
Diabetes is a collection of symptoms that arise in a person caused by an increase in blood glucose levels due to a progressive decrease in insulin secretion on the background of insulin resistance. One of the factors of diabetes is eating patterns that are irregular and do not fu [....] » Read More
Dyslipidemia is the most common major modifiable risk factor for ASCVD. Low-density lipoprotein cholesterol There is unequivocal evidence that LDL-C is causally related to atherosclerosis. The era has come when we are able to stabilise the plaque, arrest [....] » Read More
Dyslipidemia is the most common major modifiable risk factor for ASCVD. Low-density lipoprotein cholesterol There is unequivocal evidence that LDL-C is causally related to atherosclerosis. The era has come when we are able to stabilise the plaque, arrest [....] » Read More
Background: Diabetes Mellitus is common metabolic disease worldwide. The prevalence of diabetes has been shown to increase especially in developing countries, over the last decades. OBJECTIVES: To assess the pattern of diabetic admissions, indications, chronic complications, co m [....] » Read More
Background: This work is to evaluate the frequency of diabetic retinopathy, and to assimilate its impact in young diabetics followed at the endocrinology-diabetology department at the Children's Hospital of Rabat. Thus, patients with this complication were compared to patient [....] » Read More
The objective of our work is to study the relationship between glycemic control and metabolic outcomes (severe hypoglycemia and ketoacidosis). Material and Methods: Among 538 diabetics, we identified 69 patients with hypoglycemic or ketoacid comas. The HA1c assay was performed [....] » Read More
When glucose-1phosphate is added to a primer in presence of an enzyme, starch phosphorylase the glucose molecules produce a polymer amylose. I suggest recreation of this in vitro reaction complex into in vivo set of reactions, removing excess toxic glucose molecules from the cell [....] » Read More
Title : Navigating obesity, diabetes, and behavior change: A case study of a successful physician-patient partnership
Gretchen Holmes, Memorial Hospital at Gulfport, United States
Prevalence of obesity and diabetes are on the rise and have been since 1999. Physicians are frustrated at the lack of compliance from patients around behaviour change and patients are frustrated with physicians because they often need more tools and guidance to achieve successful [....] » Read More
Title : Do the STAP Test --- Prevent the Diabetes
Madhu S Malo, Diabetic Association of Bangladesh, United States
Type 2 diabetes mellitus (T2DM), characterized by hyperglycemia (≥126 mg glucose/100 ml blood after overnight fasting) and insulin resistance, is a major global health problem. Globally, approx. 6.7 million people died from diabetes in 2021, and total health expenditure due to [....] » Read More
Title : Information Technology as an enabler for prevention and management of Diabetes Mellitus: The present and the future
Akhila Harinarayan, Information Services Group (ISG), India
The probable risk of getting diabetes or being diagnosed with diabetes is a difficult situation for any patient as they must deal with the associated complications and lifestyle changes caused by the disease. Science has progressed a lot in dealing with these complications and in [....] » Read More
Title : Artificial intelligence in insulin therapy
Arvind Bhaktavatsala, AMD PVT LTD, India
Due to the availability of a large amount of data on Type1 Diabetes(T1D) and their variety, artificial intelligence (AI) techniques are increasingly being adopted in decision support systems for insulin therapy. Some of the state-of-the-art methodologies using AI and continuous g [....] » Read More
Title : Molecular basis of diabetes mellitus
Shaik Mahmood, Deccan College of Medical Sciences, India
A group of diseases that result in too much sugar in the blood (High Blood Glucose). There are two types of diabetes, Type 1 Diabetes and Type 2 Diabetes. Type 1 Disease is a chronic condition in which the pancreas produces little or no insulin. Type 2 Diabetes a chronic condi [....] » Read More
Title : A data-driven modeling approach to predicting the risks of T2DM complications
Hsing Luh, National Chengchi University, Taiwan
The objectives of this research are to utilise competing risk methods in T2DM modeling by using patient data to subsequently evaluate which diabetic complication comes first. The analysis was performed using a simulation model of people with T2DM. The model simulated a cohort of [....] » Read More
Title : Diabetes and nutrition in Morocco
El Arbi RJIMATI, International University of Casablanca, Morocco
Non-communicable diseases (NCD) are a public health problem in Morocco. According to the WHO, they are responsible for nearly three-quarters of deaths in low- and middle-income countries. The prevention of NCD is possible by controlling the main common and modifiable risk factors [....] » Read More
Title : Knowledge of Diabetes among Communiy dwelling adults in Anambra state Nigeria
Nonye Anyichie, Anambra State College of Health Technology Obosi, Nigeria
Education is vital to increasing knowledge and improving prevention practices for diabetes among community dwelling adults. This study is on effect of health education intervention on diabetes –related knowledge and preventive practices among community dwelling adults in An [....] » Read More
Title : Defective BCAA catabolism induced by PPM1K deletion causes adipose tissue fibrosis in a mouse model
Shama, The Hong Kong Polytechnic University , Hong Kong
Introduction: Obesity and type 2 diabetes (T2D) is featured by adipose tissue dysfunction and elevated levels of the branched-chain amino acid (BCAA). Unresolved inflammation, improper extracellular matrix remodeling (fibrosis), and insufficient angiogenic potential are the majo [....] » Read More
Title : Potential role of flavin monooxygenase 3 signaling in aging related adipose tissue dysfunction
Thashma Pemmanda Ganapathy, The Hong Kong Polytechnic University , Hong Kong
Adipose tissue inflammation is instrumental in the progression of age-linked metabolic complications. It translates the enhanced secretion of proinflammatory cytokines and chemokines resulting in the increased immune cell infiltration and an accumulation of senescent-associated s [....] » Read More
Title : Diabetic retinopathy and GDM in hispanic pregnant women with toxoplasma gondii
Maureen Groer, University of Tennessee Knoxville, United States
Retinal photography was performed in pregnancy and postpartum in pregnant Hispanic women with latent Toxoplasma gondii (TG) infection (N=158) A comparison group of TG negative women (N=532) was included for data from the electronic health record (EHR).The goal & [....] » Read More
Title : Human recombinant epidermal growth factor (Heberprot P) intralesional in patients with advance diabetic foot ulcer
Aristides Lazaro Garcia Herrera, Department of Vascular Surgery of the Matanzas Medical Sciences University, Cuba
To be successful in the treatment of the Diabetic Foot Ulcer (DFU) depends on how we understand the complex and dynamic interaction of factors that contribute to chronicity of the wound, the knowledge of Molecular biology changes in the diabetic wound. The DFU will be consider a [....] » Read More
Title : Glycemic behavior between different types of training: a case study
Vitor Alves Marques, Federal University of Goias, Brazil
Type 2 Diabetes Mellitus (DM 2) is generally a defect in insulin action and secretion and in the regulation of hepatic glucose production. Exercise to treat type 2 diabetes has had positive impacts on the lives of diabetics. The aim of this study is to analyze the effects of the [....] » Read More
Title : Epidemiological profile and risk factor diabetes mellitus, hospital of port-a-piment, Sud, Haiti, January -March 2023
Berger Saintius, Field Epidemiology Training Program (FETP), Haiti
Context : Diabetes mellitus is a complex chronic disease that strikes a large fraction of the population. It is characterized by chronic hypoglycemia resulting from insulin deficiency. Diabetes is a major public health problem in Haiti, as well as among patients admitted to the H [....] » Read More
Title : Identification of candidate biomarkers for type 1 diabetes mellitus by bioinformatics analysis of pooled microarray gene expression datasets in gene expression omnibus
Feng Kevin, Silver Bamboo Health Science, United States
Background: Type 1 diabetes (T1DM) is a serious threat to childhood life and has a complicated pathogenesis. Currently, molecular mechanisms of T1DM remain largely unclear. The aim of this study was to identify the candidate genes in T1DM by integrated bioinformatics analysis [....] » Read More
Title : Whole blood EDTA c-peptide: no ice, no rush
Samreen Safdar, University Hospital NHS trust Birmingham, United Kingdom
Objectives C-peptide is a useful biomarker of endogenous insulin secretion. Strict time sensitive sample collection procedures limited its clinical utility in routine clinical care of diabetes. We studied stability of whole blood c-peptide in potassium ethyl diamine tetra ace [....] » Read More
Title : Role of C-peptide in the classification of diabetes mellitus
Samreen Safdar, University Hospital NHS trust Birmingham, United Kingdom
Objectives Traditional clinical criteria used to classify diabetes may result in misclassification. In this study we evaluated the role of routine measurement of plasma c-peptide in the classification of diabetes subtype. Methods Single centred study, included patients [....] » Read More
Title : Prevalence and associated factors of diabetic nephropathy at tikur anbessa comprehensive specialized university hospital, Addis Ababa, Ethiopia
Demiraw Bikila Gurmu, Associate Researcher, Ethiopian Public Health Institute (EPHI), Ethiopia
introduction: Given the global prevalence of diabetes, diabetic nephropathy and its consequences are among the major causes of morbidity and mortality in diabetic populations. However, the prevalence and determinants of diabetic nephropathy in Ethiopia are little studied, and wer [....] » Read More
Title : Significant association of polymorphisms in the TCF7L2 gene with a higher risk of Type 2 Diabetes in a Moroccan population
Sarah EL Hourch, University of Mohamed V, Morocco
Background and aims: Several studies have shown that genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) are highly associated with the development of type 2 diabetes mellitus (T2DM) and its associated complications in several populations. The aim of our stud [....] » Read More