Biography:

Dr. Demler is an Assistant Professor of Medicine at Harvard Medical School, Boston, Massachusetts. She holds a joint appointment as a biostatistician at the Brigham and Women’s Hospital, where she oversees the design and statistical analysis of a number of metabolomic studies and interventional clinical trials.  Dr. Demler received her Ph.D. degree from Boston University where she worked with Drs Ralph D’Agostino and Michael Pencina on the statistical assessment of risk prediction models. Dr. Demler’s current methodological research focuses on the development of rigorous analytic workflows of the analysis of metabolomics data starting with quality control procedures, signal correction, and further statistical analysis of metabolomic studies. Dr. Demler’s clinical interests include cardiovascular disease prevention, lipids, biomarker research, and women’s health. The author of several highly cited peer-reviewed publications, Dr. Demler’s research focuses on risk factors and the prevention of cardiovascular diseases. She is actively involved in the analysis of several randomized clinical trials and observational studies including Framingham Heart Study, Women’s Health Study, JUPITER trial, the VITAminD and OmegA-3 Trial (VITAL). Dr. Demler was awarded a five-year career development award (K01) from the National Heart, Lung, and Blood Institute to investigate coronary heart disease risk and metabolic profiles of individuals with discordant lipids.  Dr. Demler is also leading a project funded by American Heart Association on building a flexible predictive network using large Electronic Medical Records database from several major Boston-area hospitals.