Paulo Cesar De Morais, Speaker at Oncology Conferences

Catholic University of Brasilia, Brazil

Title : Deciphering the role of graphene quantum dots as photosensitizer agents

Abstract:

Fluorine-decorated graphene quantum dots (F@GQDs) will be herein explored as a material platform for application in photodynamic therapy (PDT). GQDs have been extensively studied in biomedical areas such as bioimaging, bio-sensing and photothermal therapy due to their superior optical and physiochemical properties. Application of GQDs in PDT has been explored lately, but currently the main challenges are inadequate singlet oxygen (1O2) quantum yield (QY), poor solubility, and biocompatibility. In this talk, the synthesis of a new class of fluorine containing GQDs (F@GQDs) will be described. The as-synthesized F@GQD sample demonstrates an average particle size below 3 nm with a fluorine doping content of around 2%. The synthesized F@GQDs show improved water solubility and biocompatibility, while emitting strong green fluorescence and QY slightly above 13%. Moreover, the photodynamic activity was successfully tested in bioassays (in vitro).

Biography:

Professor De Morais (H63), PhD, full Professor of Physics at the University of Brasilia (UnB) – Brazil up to 2013. Appointed as UnB’s (Brazil) Emeritus Professor (2014); Visiting Professor at the Huazhong University of Science and Technology (HUST) – China (2012-2015); Distinguished Professor at the Anhui University (AHU) – China (2016-2019); Full Professor at the Catholic University of Brasília – Brazil since 2018; 2007 Master Research Prize from UnB. He held two-years (1987-1988) position with Bell Communications Research, New Jersey – USA. Doctoral degree in Solid State Physics (1986) from the Federal University of Minas Gerais – Brazil. With more than 15,000 citations, He has published more than 500 papers (Web of Science), presented more than 300 international invited talks (35 countries), and filed 18 patents.