Biography:

Martina Seifrtová is an assistant professor and researcher in Department of Medical Biochemistry in Faculty of Medicine in Hradec Králové. Her research is focused on clarifying the mechanisms that regulate cell cycle arrest, DNA reparation and induction of apoptosis after application of DNA damage-inducing agents. At present, she aims to the anticancer effect of substances of natural origin, particularly of alkaloids from Amaryllidaceae family. In collaboration with other departments, she participates in the study of the antitumor effect of newly synthesized PUMA inhibitors and in the study of cytotoxicity of magnetic cores and complex thermosensitive packs.