Acute pancreatitis (AP) is a dangerous and in up to 5% of cases deadly disease with no specific cure. AP often results in development of chronic pancreatitis (CP) and increased occurrence of pancreatic cancer (PC). The most common form of PC is pancreatic ductal adenocarcinoma an [....]
Importance of randomized clinical trials aa a source for “Evidence Based Oncology” is discussed and compared with contribution of empirical clinical studies. In the early 80-ties, cure rates of conventional radiotherapy (RT) were unsatisfied, and during over 25 years [....]
Problem: The estrogen receptor α (ERα) is a major driver of breast cancer (BC), being expressed in 75% of diagnosed cases. As a result, ERα is the major therapeutic target for ERα-positive BC, with agents such as tamoxifen used to block ERα activity [....]
To be updated soon..
The aim of presentstion will to demonsrate the relationship between nosological forms of the primary and second neoplasms in patients who have undergone special treatment for cancer, and who have developed second neoplasms three and more years after the end of treatment. It [....]
Breast cancer mortality is almost exclusively due to metastatic disease. Better molecular characterization of the primary tumor is therefore crucial for a good prediction of the clinical outcome. Breast cancer cells are characterized by aberrant lipid accumulation and metabolism. [....]
Although the carcinogenesis is frequently linked to genetic background, exposure to environmental risk factors has gained attention as the etiologic agent for several types of cancer. The intrauterine microenvironment has been described as preponderant factor for offspring health [....]
To be updated soon..
Awba Dam is an important source of domestic water supply in the University of Ibadan, Nigeria where anthropogenic activities such as discharge of waste from hostels and households, as well as chemicals from laboratories are channeled. There is dearth of information on the genotox [....]
This research introduces Sorush Cancer Treatment Ptotocol (SCTP) based on successful cancer treatment methodology which has done by Dr. Somayeh Zaminpira and Dr. Sorush Niknamian in 54 cancer patients in Violet Cancer Institute (VCI), Combining Specific Ketogenic Diet (SKD)- whic [....]
Introduction: Oral mucositis (OM) is a common side effect of chemotherapy or radiotherapy used for treating head and neck cancer. Symptoms usually start 5 to 10 days after chemotherapy or 14 days after radiotherapy and include dryness, halitosis, pain, inflammation and oral mucos [....]
Introduction: The lungs are the major organ of our respiratory system. They help us to obtain Oxygen and get rid of Carbon dioxide from our body. It has been the most common cancer in the world since 1985 and the leading cause of cancer death. Worldwide it is by far the most co [....]
For a young woman, fewer drops out diagnosis can disrupt her body image, the intimacy with the partner and the ability to engage in sex. A fewer drops out diagnosis affects a person's sexual functioning, according to a research. The study, led by the University of Pune, found [....]
Introduction: Difficulties in accessing appropriate accommodation and transport is a well-documented as a major stress factor for cancer patients seeking care at Uganda Cancer Institute (Young, 2010). A recent assessment of the needs of cancer patients at Mbarara University Cance [....]
As it is obvious, nowadays cancer is one of the most common disorders all around the world and nobody can ignore the importance of getting educated about them, types, how they spread around the body and how they can be treated and also some procedures after treatment because ever [....]
My objective is to bring awareness to the skin cancer trends rising within the Diaspora. My theory is in order to reduce the mortality rate, broader effort towards public awareness and education is key. Skin lightening is a wildly popular (multi billion-dollar) global industry. T [....]
Who is a patient Navigator in Oncology? Patient Navigators are mostly cancer survivors assist cancer patients in overcoming barriers to receiving quality cancer care. Patient Navigators can address barriers to care (eg, psychosocial distress, transportation) and can reduce [....]
Background: Breast cancer is one of the most relevant malignancies among women. Molecular abnormalities in promotor region of survivin gene may account for overexpression of survivin and increased breast cancer risk. This study aimed to explore the potential association between s [....]
Introduction: Oral squamous cell carcinoma (OSCC) is the sixth common cancer in the world and 90% of all malignancies in the mouth. The aim of this study was investigation of changes in some metabolic elements of patient, s serum. Materials and Methods: In this study, th [....]
Case: A 57 year old female with a history of uterine and breast cancer s/p chemoradiation presented for cervical LEEP/cone biopsy/D&C. Her medical history was &nb [....]
Background and objective: Structural diseases of the thyroid gland are very common, predominantly female swelling. These endocrinopathy can be a benign lesion in 90% of cases and in 10% of cases be a cancer. The aim of this study was to evaluate the epidemiological profile of str [....]
Point-of-care Tool for Early Diagnosis of Ovarian Cancer
Michael Thompson, University of Toronto, Canada
High grade serous ovarian cancer (HGSOC) histologic subtypes make up the majority of epithelial ovarian cancer and 85% of cases are diagnosed at advanced stages, in which the 5-year relative survival could be as low as 20%. Unfortunately, only 20% of patients are diagnosed at sta [....]
Effects of far-infrared & terahertz onnetsu therapy on various cancers, rheumatoid arthritis and other diseases
Kazuko Tatsumura-Hillyer, Gaia Holistic Health, USA
Introduction: Onnetsu means comfortable heat. Onnetsu Therapy invented by Dr. Kazuko Tatsumura emits from a special patented ceramic; 1) Heat 2) Precise 8-10µ of vibration of Far Infrared SunRay and 3) Vibration of Terahertz. Dr. Tatsumura is the first in the world to [....]
Clinical and biological roles of fusion genes in human cancers
Jianhua Luo, University of Pittsburgh, USA
Chromosome mutations and rearrangements are some of the hallmarks of human malignancies. Chromosomal rearrangement is frequent in human cancers. One of the consequences of chromosomal rearrangement is gene fusions in the cancer genome. We have identified a panel of fusion genes i [....]
Side effect of asparaginase-based drugs for childhood all can be alleviated by galactose
Oleg Gerasimenko, Cardiff University, UK
Asparaginase-based drugs are very successful against childhood acute lymphoblastic leukaemia (ALL), however, they can induce Acute pancreatitis (AP) as a side effect and force clinicians to discontinue the treatments. AP is a frequent human disease with a substantial mortality wi [....]
Targeting cancer stem cells in solid tumors
Mohammad O. Hoque, Johns Hopkins University School of Medicine, USA
Cancer stem cells (CSCs) are subpopulations of tumor cells with the ability to self-renew, differentiate, and initiate and maintain tumor growth, and they are considered to be the main drivers of intra- and inter-tumoral heterogeneity. While systemic therapy (chemo and immunother [....]
Novel complex 3D in vitro models for cancer research and drug discovery
Margareta M. Muller, Hochschule Furtwangen University, Germany
To be updated soon..
Real-time molecular diagnosis of soft tissue tumors using water-assisted laser desorption/ionization mass spectrometry technology
Yves-Marie Robin, Oscar Lambret Cancer Center, France
A substantial number of lesions in soft tissue pathology requires diagnostic precision for adequate patient care management and follow-up. Also, margin status of surgical specimens must be unequivocally defined, preferably intra-operatively, because of the tight relation which ex [....]
Increased viral richness in colorectal cancer tissues
Luigi Marongiu, University of Heidelberg, Germany
Colorectal cancer (CRC) is a major burden for the Public Health worldwide. It has been proposed that CRC has an infectious aetiology but no statistical association has been observed between disease and microbial species. On the other hand, modification of the relative prevalence [....]
Genome-wide comparative analysis of long non-coding RNAs versus protein-coding transcripts reveals distinct expression profiles and patient survival correlations across cancer types
Paola Marcato, Dalhousie University, Canada
Long non-coding RNAs (lncRNAs) are emerging targets for the diagnosis and therapeutic treatment of cancer. LncRNAs are non-protein-coding transcripts that regulate gene expression by modulating chromatin structure or by interacting with other RNA species. Additionally, they exhib [....]
EPHA2, a promising therapeutic target for hepatocellular carcinoma
Wei Qiu, Loyola University Chicago, USA
Hepatocellular Carcinoma (HCC), a primary type of liver cancer, remains one of the deadliest malignancies worldwide. Despite decades of targeted therapy advancements, the currently approved medications for advanced HCC provide patients with limited clinical benefits. One major ob [....]
Small molecule-based probes for monitoring carbonylation in live cells
Ozlem Dilek, University of the District of Columbia, USA
Small-molecule based probes have been used to tag biomolecules site-selectively on molecular basis to enhance diagnostic approaches in cancer. We designed a small molecule-based probe which incorporated with the carbonyl moiety of biomolecules through a click reaction to form a f [....]
Neuropsychology of breast cancer patients
Kalliopi Megari, Aristotle University of Thessaloniki, Greece
Post chemotherapy cognitive impairment (PCCI), is referred to a decrease in neuropsychological performance of neurocognitive measures after chemotherapy for the treatment of cancer. Chemotherapeutic drugs are often affecting both normal and cancer cells and the cause of cognitive [....]
Clinical trial evaluating the efficacy of systemic mesenchymal stromal cell injections for the treatment of severe and chronic radiotherapy-induced abdomino-pelvic complications refractory to standard therapy
Alain Chapel, Institute of Radiological Protection and Nuclear Safety, France
The late adverse effects of pelvic radiotherapy concern 5 to 10% of patients, which could be life threatening. However, a clear medical consensus concerning the clinical management of such healthy tissue sequelae does not exist. Our group has demonstrated in preclinical animal mo [....]
AIDS related Kaposi sarcoma in Brazil
Ana Luiza de Castro Conde Toscano, Emilio Ribas Infectious Diseases Institute, Brazil
Kaposi's sarcoma (KS) is a mesenchymal tumor, caused by herpes virus type 8 (HHV-8), and a characteristic neoplasm of acquired immunodeficiency syndrome (AIDS). After the emergence of AIDS in 1980, a more aggressive form of the disease, more common among homosexual or bisexua [....]
A novel mechanism that promotes mitotic spindle formation in cancer cells
Eleni Petsalaki, University of Crete, Greece
During cell division, the mitotic spindle consists mainly of microtubules (MTs) and is essential for accurate distribution of the genetic material to the two daughter cells. Errors in spindle formation can lead to incorrect separation of chromosomes that is associated with tumori [....]
Delaying the final cut: An ATM-Chk2-INCENP pathway prevents chromatin bridge breakage in cytokinesis
George Zachos, University of Crete, Greece
Chromatin bridges are strands of missegregated chromatin connecting the anaphase poles or daughter nuclei and have been linked to tumourigenesis. In response to chromatin bridges in cytokinesis, cells delay abscission, the severing of the narrow cytoplasmic canal that connects th [....]
The generation of anti-tumour bystander killing by genetically engineered ovarian tumour cells and the influence of y-irradiation: Implications for clinical use as cancer vaccines.
Jehad Zweiri, University of Liverpool, UK
Cellular based therapeutic approaches for cancer rely on careful consideration of finding the optimal cell to execute the cellular goal of cancer treatment. Cell lines and primary cell cultures have been used in some studies to compare the in vitro and in vivo efficacy of autolog [....]
Entosis in cancer: Death or survival?
Izabela Mlynarczuk-Bialy, Medical University of Warsaw, Poland
The process of entosis is not widely known phenomenon, that can impact diagnosis and prognosis of cancer. The phenomenon is characterized by the active invasion of one cell into another and the formation of “cell in cell structures” (CIC), with the participation of Rh [....]
DNA based immunotherapy for cancer: Cell wars
Rose Anne Padua, Institut de la Recherche Saint-Louis, France
To be updated soon..
Postoperative risk decline of complications at implementation of hypodermic mastectomy with simultaneous endoprosthetics of mammary glands for patients with the mammary gland cancer
Pominchuk Denis, "Medical Center" Verum, Ukraine
Introduction: mammary gland cancer has leading positions in the structure of woman oncologic morbidity with the most world countries. Surgical interference is the obligatory stage for patients with the early cancer of mammary gland and mastectomy is required frequently. Mode [....]
Natural compounds: A gate towards better treatment of breast cancer
Rana Ahmed Youness, German University in Cairo, Egypt
To be updated soon..
The effect of artemisia vulgaris extract on breast cancer granzyme expression and tumor mass diameter
Gery Rifano Hardanto, Kariadi General Hospital, Indonesia
Introduction: Beside the combination of surgery, chemotherapy, and radiation as the mainstay treatment for breast cancer, the role of immunotherapy is also well recognized. The immunomodulatory effect of Artemisia vulgaris (mugwort) has recently been investigated biochemically. H [....]
Linking cancer mortality to clinical staging, grading and therapeutic modalities, over one decade, in oncology facilities, at tertiary care settings ,2019
Hamid Yahya Hussain, Dubai Health Authority, UAE
Background: Improving cancer survival is a key challenge identified in ‘improving outcomes: a strategy for cancer, and stage at diagnosis is highly predictive of cancer mortality, and a possible explanation for the difference in cancer survival. Objectives: To study&nbs [....]
Stage 4 liver cancer healing through reiki and mexican healing therapy
Vivek Kamath, Heal the World, India
A natural energy healing technique called Reiki (Japanese Healing Method) and Mexican healing (ancient Egyptian healing method) used to heal stage 4 liver cancer patient The efforts put in my healer was just 36 hours to heal the patient and destroy the cancer cells. Total dura [....]
Automated detection of cervical pre-cancerous using regional-based convolutional neural network
Stephen Kiptoo, Moi University, Kenya
The Classification of cervical digital images will be acquired during screening and colposopy using visual inspection with acetic acid (VIA) is an important step in automated image-based cervical cancer detection. Many of cervical images classification algorithms have been develo [....]
Show me where cancer care is. Improving access to cancer services through trained patient navigators
Kenyangi Sofia Safina, African Cancer Control Alliance, Uganda
Introduction: A cancer diagnosis often produces an overwhelming emotional response, including feelings of shock, denial, fear, anxiety, anger, grief, and depression. Because a multitude of medical tests and consultations typically are needed to determine a definitive diagnosis an [....]
Comparative evaluation of characteristics of neuropathic pain and its effect on quality of life in cancer patients in oncology ward and palliative care unit
Sathish Kottaisamy, Vardhman Mahavir Medical College,India
Technological advancements and recent discoveries in cancer therapy have decreased cancer-related mortality. But the principal objective of improving quality of life through advanced cancer treatments is compromised by poor management of pain (especially Neuropathic Pain (NP)) [....]
KLF7 promotes pancreatic cancer growth and metastasis by up - Regulating ISG expression and maintaining Golgi complex integrity
Romi Gupta, UAB, USA
Pancreatic ductal adenocarcinoma (PDAC) is the fourth- leading cause of cancer-related deaths in the United States and is expected to become the second-leading cause by 2020. The five-year disease-free survival rate for patients with PDAC is extremely low and has remained <10% [....]
2 cases of anaplastic thyroid carcinoma. The main content is that weekly paclitaxel administration for ATC can be of clinical benefit
Ryo Ikoma, Yokohama Minami Kyosai Hospital, Japan
To be updated soon..
Identification of Key Pathological Features Associated with Melanoma Survival by Artificial Intelligence NLP
Anna Lian, Brigham and Women’s Hospital/Harvard Medical School, USA
Immunotherapy has reshaped the landscape of cancer treatment, showing promising treatment responses in melanoma. Currently, there are no pathological features which consistently predict treatment responses in melanoma; existing studies have involved small cohorts and shown confli [....]