Title : Telomere in health and disease
Abstract:
The aging of the population is a major global social problem. The fundamental problem of population aging is the substantial increase in the aging population and aging-related diseases, but there is still a lack of scientific and reliable disease risk predictors. How to prevent aging-related diseases and achieve healthy aging is the common goal of many disciplines such as aging biology, geriatrics, and health management, and is a scientific measure to achieve a "healthy China". Telomere length is closely related to aging-related diseases, whether telomere length can be used as a biological indicator of health and disease risk is not scientifically conclusive. We aim to establish a health and disease risk evaluation system based on telomere length. Establish a database of telomere length distribution in different age groups by an accurate, reliable and high-throughput telomere length detection method. At the same time through the retest of telomere length, analyze telomere length as a possibility to evaluate individual health and risk prediction of aging-related diseases. We will discuss whether shortening of telomere length is a risk factor for aging-related diseases, the mechanism and technology of telomere length regulation, how telomere length can be applied in the field of health management, and whether telomere length can provide a scientific basis for the prevention and treatment of aging-related diseases.