ICC 2019

Atif A Ahme

Atif A Ahme, Speaker at Oncology Conferences
Children’s Mercy Hospitals and Clinics, United States
Title : Personalized oncologic medicine in children: Current status and future promises

Abstract:

Precision oncologic medicine is an emerging approach for cancer treatment that has recently taken giant steps into solid clinical practice. Recent advances in molecular diagnostics that can analyze the individual tumor’s variability in genes have provided greater understanding and additional strategies to treat cancers. Although tumors can be tested by several molecular methods, the use of next generation sequencing has greatly facilitated our understanding of pediatric cancer and identified additional therapeutic opportunities. Pediatric tumors have a different genetic make-up with a fewer number of actionable targets than adult tumors. Nevertheless, precision oncology in the pediatric population has greatly improved the survival of patients with leukemia and solid tumors. The use of molecular diagnostics and the application of personalized targeted therapy in pediatric cancer can best be appreciated in relapsed/metastatic tumors, integrated morpho-molecular pathology diagnosis of new brain or hematologic malignancies, initial treatment of undifferentiated malignancies, and in the work-up of cancer predisposition syndromes. Novel techniques such as nanotechnology for precise drug delivery and immunotherapy with chimeric immunoreceptors promise a new direction and herald a bright future for more successful personalized targeted therapy. Although pediatric precision oncology is in its early phase, it has already affected the lives of many patients and provided grounds for more future practical developments.

Biography:

Atif A. Ahmed is Professor and Director of Anatomic Pathology Division at the Department of Pathology of Children’s Mercy Hospitals, Kansas City, Mo, USA. Dr. Ahmed graduated from University of Khartoum in 1988, completed residency and fellowship training in Pathology and is certified by the American Board of Pathology. Dr. Ahmed published more than 50 peer-reviewed articles as well as several book chapters; and is book editor of “Anatomic and Clinical Pathology Board Review” and “Gastrointestinal Stromal Tumors in Adults and Children”. He is a Member of the Society for Pediatric Pathology, the Children’s Oncology Group, and a Life Fellow of the College of American Pathologists. He is on the editorial board of several journals

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