Abstract:
Follicular dendritic cell sarcoma (FDCS) is a rare type of sarcoma that originates from the stromal component of the germinal center of the B-follicle. Its presentation and prognosis vary, as it can be nodal or extranodal, localized or multifocal, and can be fatal in 20% of cases. Due to its rarity, FDCS diagnosis requires a high level of suspicion. Most cases have been reported in Europe or the United States, and no cases have been previously reported in individuals of Iranian descent. This case report describes a 33-year-old Iranian man with no significant medical history who presented with a palpable nodule in the neck and odynophagia. MRI revealed a mass with heterogeneous enhancement in the parapharyngeal space. Pathological examination confirmed FDCS, likely localized to a parapharyngeal lymph node with no extranodal involvement. The patient underwent radiation therapy and remained disease-free 28 months after diagnosis.
Audience Take Away Notes:
The audience will be able to review their knowledge and experiences about FDCS as it is rare. The prognosis of our case is very good with 28 months of disease-free survival and no complications. This is the first pathology report in Iran as I used IHC study for definite diagnosis which proved by our colleagues in Brescia, Italy. The patient was treated by radiotherapy and reacted with a very good response to therapy. Now, I am so proud to be first one who reported this entity in my country and I hope to present this case in a big event in USA to gather feedbacks and guidance from other colleagues
