Abstract:
Chronic idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by lowplatelet counts due to increased destruction and impaired production. A 24-year-old male fromKashmir presented with bleeding gums, nosebleeds, petechiae, and oral ulcers. Initial evaluationrevealed critical thrombocytopenia (platelets: 45,000/mm³) and positive antinuclear antibodies,consistent with ITP. Despite treatment with steroids, rituximab, and IVIg, his platelet count droppedto 1,000/mm³, necessitating laparoscopic splenectomy. A multidisciplinary approach ensuredpreoperative stability. The surgery, marked by controlled blood loss (350–250 mL), improvedplatelet counts postoperatively (75,000/mm³). This case underscores the challenges ofsplenectomy in severe ITP and the importance of comprehensive care.