HYBRID EVENT: You can participate in person at Madrid, Spain or Virtually from your home or work.

2nd Edition of International Summit on Hematology and Blood Disorders

March 20-22, 2025

March 20 -22, 2025 | Madrid, Spain
Hematology 2023

Abideen Salako

Abideen Salako, Speaker at Blood Disorders Conference
Nigerian Institute of Medical Research, Nigeria
Title : Prevalence and associated risk factors of myocardial ischaemia in children living with sickle cell disease at a tertiary hospital in lagos, nigeria: A comparative cross-sectional study.

Abstract:

Background:Myocardial Ischaemia (MI) in children living with sickle cell anaemia (SCA) is rarely reported, especially in low- and middle-income countries like Nigeria. The occurrence of MI among children living with this disease could portend untoward outcomes on their quality of life and survival. The aim of this study was to determine the prevalence and associated risk factorsof MI in children aged six months to 18 years living with SCA during a vaso-occlusive crisis (VOC) compared with those in steady state at the Lagos University Teaching Hospital.
Materials and methods:This prospective cross-sectional comparative study was conducted to determine the prevalence and associated risk factors of MI among 125 children living with SCA in VOC aged six months to 18 years and 125 age and sex-matched controls in steady state. MI was determined using cardiac troponin T (cTnT) and electrocardiography (ECG) assessment. Statistical significance was set at p-value < 0.05 (95% confidence interval).
Results:The prevalence of MI using cTnT alone in children with SCA during VOC and steady state was 42.4% and 23.2%, respectively. Comparatively, using ECG alone, the prevalence of MIin VOC and steady state was 40.8% and 20.8% respectively. The prevalence of MI using both cTnT and ECG in children with SCA in VOC and steady state was 38.4% and 20%, respectively.Increasing age, lower haematocrit, elevated white blood cells and platelet count and were significantly associated with myocardial ischaemia in participants with SCA.
Conclusion:The study affirms that MI occurs in children with SCA during VOC and in steady state. The prevalence of MI is higher during VOC using either or combined cTnT and ECG. Olderage, low PCV, increased white cell counts and platelet counts are associated risk factors for MI.

Audience Takeway:
The audience will have the unique opportunity at learning
1. knowing the burden and associated risk factors of Myocardial Ischaemia/Injury among children and adolescents living with Sickle cell Anaemia using cardiac troponin T and electrocardiography in accordance with the WHO and European Society of Cardiology recommendations.
2. The outcome will help educate the audience on the need for Routine evaluation of cardiac function using ECG or cTnT levels to promptly diagnose and avert associated short or long-term cardiovascular injury or end-organ damage with detrimental health outcomes

Biography:

Dr Salako Abideen studied Medicine and Surgery at the Ladoke Akintola University of Technology, Oyo Nigeria. He then proceeded to residency training in Paediatrics and Child Health at the Lagos University Teaching Hospital, Lagos Nigeria where he bagged the Fellow of the West African College of Physicians (WACP)(Paediatrics). He had a one-year fellowship in Paediatric Haematology and Oncology at the Tata Medical Centre in Kolkata India (2015-2016). Dr Salako is currently a research fellow/consultant Paediatrician at the foremost research institute; the Nigerian Institute of Medical Research. He has published more than 20 research articles in peer-reviewed journals.

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