Title : Quality of life among leukemia patients in yemen
Abstract:
Background: Identifying and understanding the factor that influence health-related quality of life (HRQOL) in patients with leukemia is critical to creating more appropriate clinical, counseling, and social support programs to develop treatment results for these individuals. The purpose of this investigation is to examine the factor that are related with HRQOL in leukemia patients in Yemen.
Methods: From June to September 2021, a descriptive, cross-sectional investigation was carried out among Leukemia patients who attended at the pediatric leukemia units of Al-Kuwait University Hospital in Sana’a. a total of 344 individuals with Leukemia between the ages of 5 and 18 years old. Data were gathered by utilizing the Pediatric Quality of Life 4.0 as face to face interview with children and their parents. The scale consisted of four domains (Physical, emotional, social, and school functioning) and other related demographic and clinical characteristics of the patients.
SPSS was used for analyzing the data. Patient characteristics were reported as percentages, means, and standard deviations, with the mean being the most significant. As a measure of HRQOL, both the overall HRQOL score and the summary HRQOL scores were reported as mean and standard deviation coefficient tests as appropriate. Two-tailed, p-value <0.05 was regarded statistically considerable.
Results: The findings of the investigation displayed that the Leukemia patients were males with a percentage of (54.9%)The total HRQoL mean score was found to be (50.6±16.5) with the highest mean scores in the social (69.3±20.2) and emotional (55.9±20.7) functioning domains. There was correlation between age, education, residency, and total HRQoL scores, which was statistically significant (P-value<0.05). There was correlation between pre-transfusion Hb level, received chemotherapy , and total HRQoL scores (P-value<0.05).
Conclusions: Appropriate programs focused at providing psychological support to leukemia patients are needed to improve their HRQOL. The results also supported the significance of keeping a hemoglobin level of at least 9-10.5 g/dL prior to the transfusion procedure.
keyword : Leukemia, quality of life, Yemen