HYBRID EVENT: You can participate in person at Singapore or Virtually from your home or work.

2nd Edition of International Conference on

Materials Science and Engineering

March 28 -30, 2022 | Singapore

2021 Speakers

Plasma-processed nanofibrous electrospun mats as functional scaffolds or drug delivery systems

Lenka Zajickova, Speaker at
Brno University of Technology, Czech Republic
Title : Plasma-processed nanofibrous electrospun mats as functional scaffolds or drug delivery systems

Abstract:

Regenerative medicine stands before the problem to replace non-functional tissues or improve the wound healing. Therefore, many laboratories try to develop resorbable tissue scaffolds that could support the patient´s cells or breathable wound dressings that could immobilize biocide particles. The scaffold material should be biocompatible, biodegradable, and easy to manufacture, thus economically viable. A possible answer is to produce a structure made of a biodegradable polymer that mimics extracellular matrix (ECM), which would be peacefully received and gradually degraded when the new tissue has formed. The solution for wound dressings can also benefit from the nanofibrous structures that have bioactive surface able to immobilize biomolecules and particles. One of the promising polymers is FDA-approved polycaprolactone (PCL) due to its relatively low cost, excellent processability and mechanical properties, non-toxicity and low immunogenicity. However, the pristine form of PCL has a bioinert and hydrophobic surface causing problems with protein adsorption resulting in reduced cell adhesion. PCL nanofibrous mats can be efficiently modified by plasma polymerization. It leads to the formation of bioactive surface exhibiting increased cell attachment and proliferation. It offers also a possibility to attach proteins or blood platelets. In this contribution, various aspects important for plasma processing of polymer nanofibrous mats we will be discussed and the promising results will be demonstrated.

Biography:

Lenka Zajickova received her Ph.D. in plasma physics from the Masaryk University in Brno (Czech Republic) in 1999. She stayed as a post-doc at Ruhr University Bochum, and University of Minnesota in Minneapolis. She currently works at Central European Institute of Technology and Faculty of Science, Masaryk University, as an associate professor. Osaka University appointed her as a visiting professor. She published 133 papers in plasma processing of materials, bioapplications, and carbon nanomaterials. She chairs Technology Advisory Committees for Plasma Processing and Atomic Layer Processing at Society of Vacuum Coaters and the Czech representative to IUPAP Commission for Plasma Physics.

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