Title : Targeted Vesicular Drug Delivery Insight
Abstract:
Vesicles are the amphilic structure having aqueous core at the center. These vesicular drug delivery systems(VDDS)have found to be more valuable for controlled drug delivery, generally classified as Lipoidal biocarriers (e.g. Liposomes, ethosomes and transfersomes) and Non-lipoidal biocarriers (e.g. Niosomes, elastic niosomes and polymersomes) in which lipids and amphilic compounds other than lipids are used as main membrane forming components respectively. The 'liquid-state' vesicles (elastic) are more efficient in drug transport than 'gel-state' vesicles (rigid). The transfersomes, ethosomes and elastic noisomes are ultra- flexible carriers indicated for good skin permeation. Several studies have demonstrated that both processing and composition parameters are the key factors in deciding lamellar configuration, entrapment of the drug and stability aspect of dispersion system.
In the present talk like to cover the composition, application case studies ofof some of the novel targeted VDDS like pharmacosomes in ophthalmic treatment, Colloidosomes as polymeric microcapsules, Polymerasomes in migraine treatment, elastic niosomes in transdermal drug delivery, Herbasomes with better stability profile, Spingosomes as alternative to liposomes