John K Maesaka, NYU Langone Hospital Long Island, United States
Application of pathophysiologic tenets has created significant changes in our approach to hyponatremia and hyponatremia-related conditions. This approach incorporated the determination of fractional excretion (FE) of urate before and after the correction of hyponatremia and the r [....] » Read More
Title : Liver biopsy handling of Metabolic-Associated Fatty Liver Disease (MAFLD): The children's hospital of eastern Ontario grossing protocol
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Introduction: Metabolic-(non-alcoholic) associated fatty liver disease (MAFLD/NAFLD) has increasingly become a worldwide epidemic. It has been suggested that renaming NAFLD to MAFLD is critical in identifying patients with advanced fibrosis and poor cardiovascular outcomes. There [....] » Read More
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets. Discovery of agonists and antagonists of OR51E1, an understudied G Protein-Coupled Receptor
Vladlen Slepak, University of Miami, United States
Over 30% of pharmaceuticals act on G protein-coupled receptors (GPCRs), the largest family of human genes (~800). About 50% of GPCRs (~400) are Olfactory receptors (ORs); these GPCRs were originally discovered in the nasal epithelium, where they mediate the sense of smell. [....] » Read More
Title : Revolutionizing healthcare and pharma: Artificial intelligence-powered scientific communications and medical writing
Alessandro Gallo, Springer Healthcare, Italy
Recent advancements in artificial intelligence (AI) are transforming pharmaceutical research and communication. AI tools now play a crucial role in study design, data analysis, and manuscript drafting, significantly enhancing efficiency and analytical rigor. These technologies en [....] » Read More
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model to be set up via biodesign-driven biotech and upgraded biomarketing to secure the human healthcare and biosafety
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Traditionally a disease has been defined by its clinical presentation and observable characteristics, not by the underlying molecular mechanisms, pathways and systems biology-related processes specific to a particular patient (ignoring persons-at-risk). A new systems approach to [....] » Read More
Title : Preparation and characterization of fibers made from PCL/PVP-ChAgG, along with exploring their potential as wound dressings
Luis Jesus Villarreal Gomez, Autonomous University of Baja California, Mexico
Wound dressings serve to clean, cover, and shield wounds from external elements, impacting healing time, cost-efficiency, and patient well-being. Electrospun fibers offer promise in this realm due to their diverse attributes such as biocompatibility, biodegradability, mechanical [....] » Read More
Title : Emerging formulation and delivery applications of vitamin E TPGS
Andreas M Papas, East Tennessee State University, United States
Vitamin E TPGS (d-α-tocopheryl polyethylene glycol 1000 succinate) combines the functions of solubilizer, emulsifier, and absorption enhancer of lipophilic and poorly soluble drugs. In addition, it enhances drug bioavailability and efficacy through inhibition of the P-glyco [....] » Read More
Title : Genetic keys and nano locks: Unlocking personalized medicine
Srividya Narayanan, Northeastern University, United States
This presentation will explore the cutting-edge intersection of pharmacogenomics and nanomedicine, highlighting their combined potential to revolutionize drug delivery and personalized medicine. I will discuss how nanomedicine techniques are being leveraged to create targeted dru [....] » Read More
Title : Aqueous dispersions of organogel nanoparticles and porous materials as water insoluble drug delivery systems
Sophie Franceschi, University Toulouse III - Paul Sabatier, France
Organogels are semi-solid systems, in which an organic liquid phase is immobilized by a three-dimensional network. The self-organization of low molecular mass organic gelator by non-covalent interactions form fibrous structures responsible for the gelation process. The organogels [....] » Read More
Title : Evaluation of sperm immobilization factor from staphylococcus aureus as a potential candidate for male contraception
Vijay Prabha, Panjab University, India
Despite significant advances in contraceptive options for women, vasectomy and condoms are the only options available for male contraception. Due to this limitation, the burden of contraception resides on the shoulders of females only. Therefore, there is an urgent need to develo [....] » Read More
Title : Innovative approaches in novel drug delivery systems: Enhancing efficacy and targeted therapy
Siraj Khan, Qarshi Industries, Pakistan
The development of novel drug delivery systems (NDDS) represents a transformative advancement in pharmaceutical sciences, aimed at enhancing the precision, efficiency, and safety of therapeutic interventions. This research explores state-of-the-art NDDS, including nanoparticle-ba [....] » Read More
Title : Improving vaccine response through probiotics and micronutrient supplementation: Evaluating the role of TLR5 in adult female BALB/c mice
Zohre Eftekhari, Pasteur Institute of Iran, Iran (Islamic Republic of)
The role of probiotics and micronutrients in improving immune system function and response to vaccination has been proven. Hence, this study aimed to investigate the effects of probiotics enriched with micronutrients on the immunogenicity of PastoCovac® vaccine. The pro [....] » Read More
Title : Enhancing mental health for peak performance in the pharma Industry
Adam Elnekaveh, Strive to Defy, United States
In recent years, the pharmaceutical industry has witnessed remarkable advancements and innovations, shaping the future of healthcare delivery. However, amidst this progress, the well-being of industry professionals often takes a backseat. Our presentation will delve into the impo [....] » Read More
Title : Applications of our LitAr material for treatment of various diseases
Valyaev Alexander, Russian Academy of Sciences, Russian Federation
Will be Updated Soon...
Title : An overview of the impact of real-world data on signal detection
Philip Sheridan, Oracle Life Sciences, Ireland
Signal Detection in pharmacovigilance is pivotal in understanding the benefit-risk profile of medicinal products throughout their life cycle. This is an evolving discipline and has undergone multiple changes driven by both new signal detection approaches and the availability of n [....] » Read More
Title : Assessing the cancer-fighting ability of a nanodressing containing Hesperetin on Graphene Oxide Nano-Plate (HSP-GO) to target colon cancer cells through controlled drug release
Arezou sabbagh hadi, Tabriz university, Iran (Islamic Republic of)
Will be Updated Soon...
Title : Insights into non-natural peptide aggregation: Accelerated molecular dynamics (amd) for biocompatible material design
Ahmed Saeed, University of Milan, Italy
In the last year, an increasing interest has been observed toward the design of small molecules that can self-assemble to form supramolecular structures. In particular, peptides gain attention due to their unique qualities like being friendly to living organisms, conducting elect [....] » Read More
Title : MMPs (Matrix Metalloproteinases) -Responsive ‘smart’ nanomedicine in cancer treatment
Jing Zhang, Technical University of Denmark, Denmark
The overexpression of specific matrix metalloproteinases (MMPs) is a hallmark of many cancers, making these enzymes ideal targets for the development of stimuli-responsive nanomedicines. In this context, MMP-responsive ‘smart’ nanomedicine has been engineered to deliv [....] » Read More
Title : Ferrocene modified imatinib and niotinib analogues as novel tyrosine kinase inhibitors
Georgi Stavrakov, Medical University of Sofia, Bulgaria
Ferrocene (Fc) is an 18-electron organometallic complex composed of a central iron(II) ion sandwiched between two parallel cyclopentadienyl (Cp) ligands. Due to its unique geometry and chemical features, the Fc moiety has been an enticing research subject in organometallic, mater [....] » Read More