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Luis Jesus Villarreal Gomez, Speaker at Pharma Conferences
Autonomous University of Baja California, Mexico
Title : Preparation and characterization of fibers made from PCL/PVP-ChAgG, along with exploring their potential as wound dressings


Wound dressings serve to clean, cover, and shield wounds from external elements, impacting healing time, cost-efficiency, and patient well-being. Electrospun fibers offer promise in this realm due to their diverse attributes such as biocompatibility, biodegradability, mechanical strength, and moisture control. Incorporating antimicrobial properties is crucial, hence, this study aims to develop wound dressings using functionalized electrospun nanofibers of poly (caprolactone)/poly (vinyl pyrrolidone) (PCL/PVP) blended with a nanocomposite of Chitosan/Silver Nanocrystals/Graphene Oxide (ChAgG). ChAgG combines Chitosan from corn, silver nanocrystals from garlic, and Graphene Oxide. These fibers were functionalized with varying proportions of ChAgG nanocomposite solution through blending electrospinning. Characterization via techniques like FTIR, XPS, and TEM confirmed the composition of the nanocomposites. Scanning electron microscopy assessed fibrous dressing morphology and diameter, while thermal analyses and FTIR demonstrated ChAgG incorporation into the polymeric matrix. Mechanical testing favored fibers with 5% ChAgG for wound dressing applications. Antibacterial assays highlighted improved efficacy against Escherichia coli over Staphylococcus aureus. Future endeavors may involve biocompatibility studies and animal testing to further validate the system's efficacy, paving the way for an optimized, antimicrobial wound dressing with market competitiveness.


Dr. Luis Jesus Villarreal Gomez, studied Chemistry-Biology at the University of Sonora, Hermosillo, Mexico and graduated in 2004. He then received his PhD degree in 2013 at the University Autonomous of Baja California, Tijuana, Mexico where he joined as full research professor. Dr. Villarreal is founder and editor in chief of the Revista de Ciencias Tecnologicas (RECIT) (ISSN 2594-1925) and is editorial board member of several journals edited from MDPI, Hindawi, BenthamOpen, amongst others. Until now, he been published 32 papers and have been reviewed more than 120 reviews. His research lines are biomaterials, tissue engineering, drug delivery systems and biotechnology.