Patrizia Ferretti is Professor of Regenerative Biology at UCL Great Ormond Street Institute of Child Health, London, UK. She studied at Pisa University and at the Mario Negri Institute for Pharmacological Research, Milan, Italy, prior to moving to the Max Planck Institute, Goettingen, Germany, and then to London. She is interested in mechanisms governing tissue repair within the context of normal and abnormal development of the nervous system and of craniofacial structures.Over the years her group has made a sustained and internationally recognized contribution to the regeneration field. They have identified a number of cellular and molecular mechanisms which play a role in response to injury and repair and established models to study human diseases using stem/progenitor cells. Current work focused on engineering skeletal tissue and modelling human rare diseases using stem cells continues to implement the successful strategy of addressing basic biological questions and harnessing the information acquired to develop therapeutic approaches.