HYBRID EVENT: You can participate in person at Singapore or Virtually from your home or work.

10th Edition of International Conference on
Dentistry and Oral Health

March 13-15, 2025 | Rome, Italy
Dental 2022

Balamurugan R

Balamurugan R, Speaker at Dental Conferences
RYA COSMO Foundation, India
Title : Evaluation and comparison of anti-inflammatory properties of Ibuprofen using two drug delivery system after third molar surgery- Using chitosan microspheres as a carrier for local drug delivery in to the third molar socket and through oral route

Abstract:

This study was to assess the analgesic and anti-inflammatory properties of ibuprofen when administered through two drug delivery systems after mandibular third molar surgery. The study was conducted on 100 patients who required the surgical removal of impacted mandibular third molars under local anaesthesia. The study subjects were divided into two groups of 50 patients each. Patients in the study group were given ibuprofen-incorporated chitosan-based microspheres, which were packed into the third molar sockets after removal of impacted teeth. Patients in the control group were prescribed with ibuprofen 400mg tablets that were to be administered orally after the removal of impacted mandibular third molars. All patients were assessed for pain, swelling, and trismus on the second, fourth, and seventh postoperative days, and wound healing was assessed on the seventh postoperative day. Patients in the study group had significantly less pain and comparatively better mouth opening on the second, fourth, and seventh postoperative days, which showed clinically and statistically significant results of p<0.05, respectively, while the assessment of swelling for the study group did not show statistically significant results on any of the three postoperative days. Among 50 patients in the study group, two had wound gaping, and among 50 patients in the control group, four presented with wound gaping and three patients developed dry socket. Ibuprofen-incorporated chitosan-based microspheres (study group) had comparatively better analgesic and anti-inflammatory properties with drastic reduction of pain, swelling, trismus, and also had a reliable wound healing property when compared with the orally-administered ibuprofen (control group) after mandibular third molar surgery.

Biography:

DR.BALAMURUGAN.R is an Oral and Maxillofacial Surgeon and Oral Implantologist from Chennai, India. He initiated his professional career in the field of dentistry and continued his specialisation in the path of Oral and Maxillofacial Surgery (India) and Fellowship in Oral Implantology (International Congress of Oral Implantologists ICOI, USA). His field of expertise in basic dental treatments, dento-alveolar surgeries, maxillofacial trauma, dental implants, medical emergencies, pathologies associated with maxillofacial region, TMJ related disorders. He was awarded as the best PEER REVIEWER by Star Dental Centre Pvt Ltd, India for his sincerity and dedication towards work by adhering to the timelines with a prompt reviewing process. He holds various International and National peer reviewed paper publication that adds credit to his career. He is associated with International and National journals as editor and reviewer board member and he has also been invited as a keynote speaker globally. He also encourages and motivates the authors to explore with new innovative ideas in the field of research. Currently, he is a researcher and walks in the right path of motivation by providing a heart of service for the patients as an Oral and Maxillofacial Surgeon in RYA Cosmo Foundation, Chennai, India.

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