HYBRID EVENT: You can participate in person at Orlando, USA or Virtually from your home or work.

7th Edition of International Conference on
Dentistry and Oral Health

April 27-29, 2023 | Orlando, USA
Dental 2023 Speakers

Elaheh Dalir Abdolahinia

Elaheh Dalir Abdolahinia, Speaker at Dental congress 2023
Research Center for Pharmaceutical Nanotechnology, Iran (Islamic Republic of)
Title : Stem cell homing for regenerative endodontics in nano composite hydrogel patterns


Clinically, functional pulp-like tissue should be capable of producing vascularized and re-innerved tissue that controls the amount of dentin deposition in dental tissue. In this situation, the pulp regenerates close to the healthy pulp. About 50 years ago, Nygaard-Ostby evaluated the hypothesis that blood clots have healing effects in the treatment of damaged tooth pulp. The findings revealed that the blood clot in the pulp tissue of the tooth did not regenerate entirely. Subsequent studies showed that by intentional bleeding into the root canal in immature necrotic teeth, living tissue regenerated, which was associated with neural network sensitivity. Cell homing is an underappreciated approach to tissue regeneration that provides an alternative to cell-delivery-based tooth regeneration and appears to provide a tangible pathway toward clinical translation. Dental stem cells would be a suitable candidate for endogenous stem cells for dental tissue regeneration. Cell-homing approach based on stem cells residing in the oral tissue regenerates new like-pulp with the help of growth factors secreted from the engineered scaffold that can overcome all cell transplantation strategy’s challenges. Hydrogel scaffold can be a suitable substrate for dental stem cells to recruit, proliferate, and differentiate. For example, it was proven that a designed peptide-based hydrogel with bFGF for injection into the root canal could serve as a carrier of different molecules as well as a good substrate for the growth of target tissue cells. It may also be used to combine soft and hard tooth tissue to regenerate endodontics. 


Elaheh Dalir Abdolahinia studied Biotechnology at Zanjan University, Zanjan, and graduated an MS in 2008. She then joined the research group of Prof. Omidi at Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute (RCPN), Tabriz University of Medical Sciences (TUoMS), Iran. She received her Ph.D. degree in 2019 in the Medical biotechnology field at the Zanjan University of Medical Sciences (ZUMS). After two years of postdoctoral fellowship supervised by Prof. Barar at the RCPN, she obtained the position of Research Associate at RCPN, Iran. She has published more than 30 research articles in Scopus journals. Since 2020, she has focused on cell therapy to regenerate damaged tooth tissue.