Title : Advanced Smart nanobiomaterials as emerging versatile platforms for healthcare systems
Abstract:
High quality materials in the nanosize and based-platforms have advantages over conventional methods due to feasibility of tailoring and tuning the desired properties to produce enhanced uniform distribution, targeted and localized delivery, sustained and controlled release, and enhanced therapeutic efficacy with fewer side effects. The synthetic articulation can be achieved in their shapes and sizes that modulates the unique physicochemical properties to achieve the desired properties for a variety of biomedical applications. A multitude of synthetically produced nanoparticles from inorganic/metallic nanoparticles (carbon, iron oxide and gold), organic (dendrimers, polymers) and inorganic/organic nanocomposites are explored in our group to build a biocompatible, biodegradable architecture for attaining multifunctional and multimodal approaches to suffice from targeting and delivery, tissue engineering and molecular bio-imaging. Most of these inorganic/metallic nanoparticles are stabilized with various synthetically articulated simple to complex organic ligands which hold the capacity for multifunctional groups for various applications such as physiological circulation and stealth, targeted delivery, molecular recognition and non-invasive multimodal approaches. This presentation highlights some of the properties of the nanomaterials and complex ligand designs and their structures using which the selective delivery systems, tissue engineering and multimodal imaging platforms are developed for effective diagnosis and therapy.
