Title : An updated review on microsponges
Abstract:
Microsponges drug delivery, because of their benefits has got a lot of potential and is very emerging field have been leading researchers around the globe to investigate them as drug carrier. Microsponges are polymeric drug delivery system composed of porous microspheres. They are tiny sponge like spherical particles with large porous surface. This unique technology for controlled release topical agents also use for oral as well as biopharmaceutical drug delivery. Microsponge are reliable delivery system that encapsulate both water insoluble and water sparing agent to improve their effectiveness. Microsponges can entrap various types of drugs and encorporated in formulations like cream, gel, lotion and powder. Various marketed formulations are also available Cerac, Ultraguard and retinol cream . One of the best feature of this technology is that that its own self- sterilizing and it provides increased efficacy for topically active agents with enhance formulation flexibility and numerous study has confirmed that microsponges are non-mutagenic, non-irritant and non-allergic in nature. The current review elaborates the microsponges technology with its release mechanism, preparation methods, characterization, evaluation parameters and its applications.
