Keynote Presentation
Hans Christian Siebert, Research Institute of Bioinformatics and Nanotechnology (RIBNT), Germany
The global outbreak of SARS CoV2/ Covid19 is a great challenge for new concepts and strategies in different fields as glycobiology, nanomedicine or nanopharmacology. When correlating clinical data obtained from patients in intense care units with tools used in structural biology [....] » Read More
Title : Synergism in the permeability of the blood-brain barrier of heavy elements under the influence of electromagnetic fields.
Bartolome Ribas Ozonas, Royal National Academy of Pharmacy, Spain
The possible effects of electro magnetic fields (EMF) in the human body are explained because the external EMF, as a physic toxic agent, induced to a possible physiological and biochemical molecular effects as in the electron transfer chain in the mitochondria, synthesis by ATP-s [....] » Read More
Title : Rejuvenation of old drugs by repurposing, formulation and salt formation
Abraham Avi J Domb , The Hebrew University of Jerusalem, Israel
The introduction of a new drug entity to the clinic may take many years with a significant investment. Thus, only a few dozen of new drug entities are approved by the FDA each year. Chemical modification of existing drugs for improved properties or generating new IP, is considere [....] » Read More
Title : Pathology and Patient Safety: The vital role of electronic medical record and pathology informatics in error reduction and precision medicine
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Electronic medical record (EMR)'s use has increased exponentially worldwide. The traditional pen and paper way to record events and data in a patient's chart has evolved to EMR, allowing numerous opportunities. There is the potential to provide higher quality and safer ca [....] » Read More
Title : Anti-inflammatory and Anti-oxidative Effects of Febuxostat on Periodontitis Rats Model
Naseratun Nessa, Kyoto Prefectural University of medicine, Japan
Objectives: Periodontal disease is quite prevalent and affects about 20-50% of global population. Periodontitis is a chronic inflammatory disease of the supporting structures of the teeth. When periodontal pathogens enter into the blood stream, such lifestyle diseases develop. Fe [....] » Read More
Title : Nano modification of Antrodia cinnamomea exhibit anti-inflammatory action and improves the migratory potential of myogenic progenitors
Mridula Prakash Menon, National Ilan University, Taiwan
Skeletal myogenesis involves the formation of new skeletal muscular tissue. During an injury, the skeletal muscle stem cells known as the satellite cells get activated and undergo proliferation, migration, and differentiation to complete the process of myogenesis. Muscle wasting [....] » Read More
Title : Dendrobium nobile Lindl. alkaloids-mediated protection against Aβ25-35-induced synaptic deficits is dependent on activation of Wnt/β-catenin pathway in rats and in cells
Wei Zhang, Guizhou University, China
Synaptic degeneration, associated mitochondrial dysfunction and accumulation of amyloid-β peptide are considered as the important manifestation which leads to cognitive impairment and memory loss in Alzheimer’s disease (AD)-affected brain. Avoiding the early characteri [....] » Read More
Title : Statistically Designed Terbinafine Hydrochloride Ethosomal Gel for Enhancement of Transdermal Delivery: In-silico Molecular docking, In vitro, Ex vivo and Stability Study
Hemalata Suhasrao Dol, Bharati Vidyapeeth College of Pharmacy, India
Terbinafine HCl (TH), an allylamine antifungal (BCS-II) drug has poor solubility and high permeability. In the present work, we have investigated the potential of ethosomes as vesicular lipid nanocarrier for enhancement of transdermal application of TH. The In-silico molecular do [....] » Read More
Title : Formulation and Evaluation of Biodegradable Polymeric Scaffolds containing Mupirocin Microspheres for Improved Wound Healing
Neha Manish Munot, Vishwakarma University, India
Development of a bio-composite using synergistic combination is a promising strategy to address various pathological manifestations of acute and chronic wounds. In the present work, we have combined three materials viz., mupirocin as an antimicrobial drug, mupirocin-chitosan micr [....] » Read More
Title : Polymeric Scaffold loaded with Polyphenolic Compound as Wound Dressings: A promising approach to wound healing
Shilpa Nilesh Shrotriya, Bharati Vidyapeeth University, India
Wounds are physical injuries which result in loss of the skin surface integrity. Proper healing of wound is essential for restoration of disturbed functions of skin. In the present research, we report fabrication of polyphenolic compound loaded nanofibrous scaffold as wound dress [....] » Read More
Title : Interaction of Commonly Used Oral Molecular Excipients with P-glycoprotein
Ruchika Bajaj, University of California, United States
P-glycoprotein (P-gp) plays a critical role in drug oral bioavailability and modulation of this transporter can alter the safety and/or e?cacy pro?le of substrate drugs. Individual oral molecular excipients that inhibit P-gp function have been considered as a mechanism for improv [....] » Read More
Title : Showcasing the Quality by Design Framework on Nano Drug Delivery Systems
Suryakanta Swain, The Assam Kaziranga University, India
The Quality by Design (QbD) approach empowers the researchers to minimize the number of experimental trials, errors and time during process of formulation development. It helps to identify the significant, influential factors such as critical material attributes, critical formula [....] » Read More
Title : revolution in nanotherapeutics for treatment and management of high grade glioblastoma Multiform
Aarti V Belgamwar, Shri Vile Parle Kelvani Mandal Institute of Pharmacy, India
Intracranial malignancies represent 1.4% of diagnosed cancers and Glioblastoma multiform (GBM) is one of the most aggressive malignant tumors with an overall dismal survival averaging one year despite multimodality therapeutic interventions including surgery, radiotherapy and con [....] » Read More
Title : Development And Optimization Of Nano-Emulsion Containing Rosemary Extract As Skin Rejuvenate Agent As A Novel Drug Delivery System
Devshree Gayakwad, Acropolis Institute of Pharmaceutical Education and Research, India
The effective delivery of Herbal drugs as a cosmetic formulation with the minimum side effects and better therapeutic efficacy has remained active area of research for many decades. This study aimed to developed and optimization oil in water (o/w) nano-emulsion containing r [....] » Read More
Title : Advanced multifunctional carbon dots/porphyrins for cancer diagnosis and photodynamic therapy
Gil Goncalves, University of Aveiro, Portugal
According to the findings of this study, a novel approach has been developed to address the constraints of employing porphyrins in photodynamic treatment, which include their low solubility and aggregation in biological contexts. The conjugation of porphyrins with graphene quantu [....] » Read More
Title : Phytochemical-based nanoformulation against Hepatocellular carcinoma
Lekshmi R Nath , AIMS Health Science Campus, India
Hepatocellular carcinoma (HCC) is one of the deadliest malignancies being the 3rd leading cause of cancer death worldwide. The current treatment of HCC fails to provide tumor specificity, causing many systemic toxicities and poor overall survival benefits especially for patients [....] » Read More
Title : All-trans retinoic acid loaded chitosan lipid nanocomplex for enhancing its diabetic nephropathy healing effect
Marwa Hasanein Mohamad Asfour, National Research Centre, Egypt
The present study aims to formulate all-trans retinoic acid (ATRA) loaded chitosan lipid nanocomplex (CHLNC) for enhancing its solubility and oral delivery. This is to improve ATRA therapeutic effect on diabetic nephropathy (DN). CHLNC was prepared by o/w homogenization, employin [....] » Read More
Title : Assessment of Marquesan Rauvolfia nukuhivensis bioactive content
Phila Raharivelomanana, University of French Polynesia, French Polynesia
Rauvolfia genus, grown in tropical areas, is well-known for its many species used in traditional medicine which healing properties inspired pharmacological studies leading to successful discovery of innovative drugs through years. Finding of these drugs were directly related to e [....] » Read More