Abstract:
Most commonly used route of administration for drugs is oral route. Poor water solubility or permeability of medications, as well as a wide pH range displayed by the gastro intestinal tract, are all obstacles to oral absorption.Hypertension, which is currently a worldwide epidemic, is a risk factor for significant cardiovascular disorders such as myocardial infarction, stroke, heart failure, and peripheral artery disease.
Although multiple medicines operating through various mechanisms of action are available in conventional formulations for the treatment of hypertension, they confront significant hurdles in terms of bioavailability, dose, and related side effects, all of which restrict their therapeutic efficacies.Studies have shown that incorporating a medicine into a nanocarrier can improve drug bioavailability while also lowering the toxicity associated with high therapeutic doses. The current review discusses the difficulties with traditional antihypertensive formulations and the necessity for oral nanoparticulate systems. They can be used for targeted drug delivery, in treatment of cancer,in cosmetic and agro food industry also so Nanocarrier system is a great challenge over conventional formulation to reduce the problem related with other formulation.
Biography:
Ashwini V.Jadhav is currently working in department of Pharmaceutics at GSM, college of Pharmacy Wagholi, Pune ,Maharashtra.she has total 12 year academic and one year industrial experience. She obtained her M.Pharm in Pharmaceutics from SPPU, pune university India in 2014 and perusing PhD from VISTAS,Vels university, Chennai,Tamilnadu,India.She has more than 10 years of research experience with over 30 national and international publications. She has approved Teacher from SPPU and MSBTE governing Body. She worked as research coordinator in the institute. She has guided around 5 M.pharm students.Her research areas for interest includes nanocarries development, advance drug delivery system for pediatric patient, design of targeted drug delivery systems.Ashwini V.Jadhav is currently working in department of Pharmaceutics at GSM, college of Pharmacy Wagholi, Pune ,Maharashtra.she has total 12 year academic and one year industrial experience. She obtained her M.Pharm in Pharmaceutics from SPPU, pune university India in 2014 and perusing PhD from VISTAS,Vels university, Chennai,Tamilnadu,India.She has more than 10 years of research experience with over 30 national and international publications. She has approved Teacher from SPPU and MSBTE governing Body. She worked as research coordinator in the institute. She has guided around 5 M.pharm students.Her research areas for interest includes nanocarries development, advance drug delivery system for pediatric patient, design of targeted drug delivery systems.
