Mitali Bodhankar

The state of one's skin has been said to represent one's overall health and age. Nutrition and its effects on the skin have raised the interest of scientists and clinicians around the world for ages. One of the elements that contribute to overall skin health is nutrition. Skin's structural integrity and biological function are affected as a result of poor nutrition, resulting in an aberrant skin barrier.  These nutrients are used as ingredients in cosmetic products as well as active compounds in therapeutic agents for treating certain skin disorders. The novel drug delivery systems can be effectively used for treatment of skin in various skin conditions. The carrier based drug delivery like liposomes, ethosomes, niosomes, lipospheres, microsponges, solid lipid nanoparticles etc. are used to treat skin problems as well as for skin health and nutrition. Proliposomes are more effective over liposomes as they overcome the drawback of instability. Ethosomes are also more effective because of better penetration because of its composition. The formulations containing drugs and nutrients were prepared and were analyzed for particle size, permeation, zeta potential and stability. The study shows the best use of these Novel drug deliveries in conditions like acne and hyperpigmentation. Topical administration of probiotic bacteria Lactobacillus acidophilus alongwith proliposomes of the drug modulates immunity and affects keratinocytes when administered topically. Ethosomal gel formulation of Vit A and Vit C helps in deeper penetration in Hyperpigmentation. Also the drug Hydroquinone and Vit A included in ethosomes and vit C in gel formulation give better results.