End-of-life care in cancer patients requires compassionate, patient-centered approaches that address both physical symptoms and emotional well-being. Hospice care focuses on providing comfort and dignity when curative treatments are no longer effective, with a team of doctors, nurses, social workers, and chaplains offering holistic support. Ethical issues, such as decisions around life-sustaining treatments, must be carefully considered, often involving conversations between patients, families, and care providers. Clear and open communication ensures that patients' wishes are honored while providing families with the support they need during difficult times. This approach helps alleviate suffering, offering patients a peaceful transition and giving families guidance through the grieving process.