Oral manifestation of gardeners syndrome

Gardener syndrome is a subtype of familial adenomatous polyposis. It is inherited in an autosomal dominant manner, caused by a mutation in the APC gene and characterised by adenomatous polyps of the gastrointestinal tract, desmoid tumours, multiple osteomas, epidermoid cysts, lipomas, periampullary carcinomas and dental abnormalities such as odontomas and supernumerary teeth. These growths, called polyps are noncancerous at first, but some have a 100% chance of becoming cancerous. This patient presented at a University Dental Hospital, following referral from her GDP as she struggling to eat with her current dentures. Due to the inability to chew her food effectively, she is having resultant bowel blockages. After performing an examination a treatment plan was formed, involving the need for endodontic treatment, replacement of leaking restorations and provision of upper and lower partial dentures. This presentation will discuss the oral manifestations of Gardeners Syndrome and how this can affect our treatment planning options when restoring a patient’s dentition and considering space replacement.