Personalized and Precision Medicine (PPM) through biodesign inspired translational applications and the integration of dentistry into interprofessional healthcare to secure human oral health and biosafety

Title : Personalized and Precision Medicine (PPM) through biodesign inspired translational applications and the integration of dentistry into interprofessional healthcare to secure human oral health and biosafety

Abstract:

Advances in the foundational science of dental, oral, and craniofacial health are expanding and enabling personalized and precision care built on strong discoveries in the fields of systems and synthetic biology, with the advances in and OMICS technologies and IT support. Modern innovations allow dentists to detect problems much earlier, treat them more precisely, and even restore smiles that would have been impossible to repair a generation ago. In this context, dictated by PPM requirements, the innovative design and advanced biointerface-related and engineering have promoted the development of various smart medicines, unique therapeutic protocols and nanocarriers for optimizing diagnostic procedures and drug delivery to monitor, to treat and to manage oral and dental diseases. The latter dictates that oral tissue engineering is considered as an interdisciplinary field of design-driven biotech that comprises applying principles of life sciences and nanobiomaterials to restore, main-tain and enhance tissue function. For instance, cellular therapy and targeted immunotherapy are key components of oral and dental tissue and immune cell engineering. Another example is protein engineering through the view of biodesign, offering significant promise for applications in tissue engineering, regenerative dentistry and plastic oral surgery. The use of advanced fabrication technologies, such as computer-aided design, 3D printing, and digital scanning, has greatly improved precision, reproducibility, and clinical efficiency. 3D printing has revolutionized how dentists create restorations such as crowns, bridges, dentures, and even aligners. The advent of nanotechnology, digital dentistry, and 3D printing has further expanded the frontiers of the field, offering new possibilities for individualized (patient-specific) treatment solutions and regenerative therapies.
The field of dentistry is undergoing a rapid transformation driven by groundbreaking technologies that enhance precision diagnosis, personalized treatment, and patient experience. As innovations become mainstream, patients benefit from PPM-guided and comfortable care than ever before, since healthcare is undergoing a transformation globally illustrating the advent of PPM. The latter would provide a unique platform for dialogue and collaboration among thought leaders and stakeholders in government, academia, industry, foundations, and disease and patient advocacy with an interest in improving the system of healthcare delivery on one hand and drug discovery, development, and translation, on the other one. The future holds even greater potential for innovation, with ongoing research into areas like nanotechnology and IT algorithms promising to further revolutionize dental care.

Biography:

Sergey Suchkov was born in the City of Astrakhan, Russia, in a family of dynasty medical doctors. In 1980, graduated from Astrakhan State Medical University and was awarded with MD. In 1985, Suchkov maintained his PhD as a PhD student of the I.M. Sechenov Moscow Medical Academy and Institute of Medical Enzymology. In 2001, Suchkov maintained his Doctor Degree at the National Institute of Immunology, Russia. From 1989 through 1995, Dr Suchkov was being a Head of the Lab of Clinical Immunology, Helmholtz Eye Research Institute in Moscow. From 1995 through 2004 - a Chair of the Dept for Clinical Immunology, Moscow Clinical Research Institute (MONIKI). In 1993-1996, Dr Suchkov was a Secretary-in-Chief of the Editorial Board, Biomedical Science, an international journal published jointly by the USSR Academy of Sciences and the Royal Society of Chemistry, UK. At present, Dr Sergey Suchkov, MD, PhD, is: Professor, and Chair of the Dept for Personalized Medicine & Precision Nutriciology of the Institute for Global Health of RosBioTech, and Professor of Dept of Clinical Immunology, A.I. Evdokimov Moscow State Medical and Dental University (MGMSU), Russia; Secretary General, United Cultural Convention (UCC), Cambridge, UK. Dr. Suchkov is a member of the: New York Academy of Sciences, USA, American Chemical Society (ACS), USA; American Heart Association (AHA), USA; European Association for Medical Education (AMEE), Dundee, UK; EPMA (European Association for Predictive, Preventive and Personalized Medicine), Brussels, EU; ARVO (American Association for Research in Vision and Ophthalmology); SER (International Society for Eye Research); Personalized Medicine Coalition (PMC), Washington, DC, USA.