2nd Edition of International Conference on Tissue Engineering and Regenerative Medicine

September 16-17, 2022 (Online Event)

September 16 -17, 2022 | Online Event
TERMC 2021

Bioprinting bioinspired microenvironments to study cell-matrix interactions

Ruben F Pereira, Speaker at Tissue Engineering Congress 2022
University of Porto, Portugal
Title : Bioprinting bioinspired microenvironments to study cell-matrix interactions

Abstract:

Bioprinting is assuming a central role in tissue engineering and regenerative medicine, enabling the fabrication of 3D constructs and in vitro tissue models with biological function. The biophysical and biochemical cues of the cell microenvironment are recognized as key variables determining cell fate and how cells respond to the surrounding niche. We have designed a toolbox of double crosslinked bioinks with tuneable and controllable cues to study the regulatory role of microenvironmental cues on cell behaviour and biological function of bioprinted constructs. Our approach involves the bioprinting of cell niches in which biophysical and biochemical cues can be independently modulated and presented to the cells in a precise manner. Our findings reveal the importance of matrix cues on cell response and their implication on the biological properties of bioprinted constructs.    

Biography:

Rúben Pereira is an Assistant Professor at Instituto de Ciências Biomédicas Abel Salazar (ICBAS, University of Porto) and Assistant Researcher at the Biofabrication Group (i3S, Instituto de Investigação e Inovação em Saúde). He holds a PhD in Biomedical Sciences with specialization in 3D bioprinting and has been collaborating with the pharmaceutical industry in the design of biomaterials for skin repair. He has also been involved in research projects in the fields of bioengineering, 3D bioprinting and tissue engineering. His research interests focus on the development of dynamic hydrogels for the bioprinting of biomimetic cell microenvironments for tissue engineering and regenerative medicine applications.

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