Luis Filipe de Oliveira Figliolino , University of Mogi das Cruzes, Brazil
Hospital services have increasingly sought the satisfaction of their clients, through which we are able to measure the quality of health care, as well as other measures of behavioral outcomes of patients1. It is believed to have a direct relationship between the degree of satisfa [....] » Read More
Title : Low angle X - ray fiber diffraction wins gold for Cancer diagnosis
Veronica James, Australian National University, Australia
Every cancer sends out a type-specific signal, as soon as it starts, thus providing the earliest possible diagnosis of the cancer by the cancer itself. These signals can be detected as specific alterations in the low angle X-ray diffraction patterns for skin and/or hair. In [....] » Read More
Title : Electrochemical point-of-care sensor for early diagnosis of Ovarian Cancer
Michael Thompson, University of Toronto, Canada
Will be Updated Soon...
Title : Digital profiling of protein and microRNA in Rhabdomyosarcoma
Atif A Ahmed, Seattle Children’s Hospital, United States
Rhabdomyosarcoma exhibits a complex prognostic algorithm based on histologic, biologic and clinical parameters. In contrast to alveolar rhabdomyosarcoma, embryonal (ERMS) and spindle cell and sclerosing rhabdomyosarcoma (SRMS) histologic types exhibit more heterogenous molecular [....] » Read More
Title : Muc-mucins of special feature in “nuclear inverse-polarity papillary lesion lacking myoepithelial cells
Shinya Tajima, National Hospital Organization, Shizuoka Medical Centre, Japan
Breast papillary lesions exhibit broad range. Tajima et al. reported in discrimination between benign intraductal papilloma (IDP) and malignant endocrine ductal carcinoma in situ (E-DCIS), new marker of CD56 is useful for discriminating between benign and malignant. Hence, detect [....] » Read More
Title : The abscission checkpoint: a protector of chromosomal stability
George Zachos, University of Crete, Greece
Increasing evidence indicates that cancer metastasis is regulated by specific genetic pathways independent of those controlling tumorigenesis and cancer growth. WASF3, a Wiskott-Aldrich syndrome protein family member, appears to play a major role not only in the regulation of act [....] » Read More
Title : The research on anti-tumor activity and its mechanism of traditional Chinese medicine Inonotus hispidus
Haiying Bao, Jilin Agricultural University, China
The mushroom Inonotus hispidus is traditional Chinese medicine, which has been used to treat tumor illness for a long history in China. I. hispidus mushroom mainly grows on five different tree species (Morus alba L., Ulmus macrocarpa Hance, Fraxinus mandshurica Rupr., Ziziphus ju [....] » Read More
Title : The CEA-specific plasmid-based CAR -T cells effectively suppress the human CEA-positive cell culture and tumor xenograft in murine model
Yana Yurevna Kiseleva, Russian Scientific Center of Roentgenoradiology, Russian Federation
The adaptation of CAR-therapy for a treatment of solid malignant tumors is currently considered as a highly promising opportunity for future therapies. One of the approaches in primary human T cell engineering effective commonly used for CAR gene delivery is retroviral gene trans [....] » Read More
Title : Immuno suppressive mediators impair pro inflammatory innate lymphoid cell function in human malignant Melanoma
Giuseppe Ercolano, University of Naples Federico II, Italy
Innate lymphoid cells (ILC) are a family of immune cells that are emerging as potent orchestrators of immune responses. In cancer, ILCs display both pro- and antitumorigenic functions depending on the nature of the tumor and the involved ILC subset. Little is known about the ILC& [....] » Read More
Title : DOT1L promotes Ovarian Cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis
Romi Gupta, The University of Alabama at Birmingham, United States
Ovarian cancer is the leading cause of gynecological malignancy-related deaths. Current therapies for ovarian cancer do not provide meaningful and sustainable clinical benefits, highlighting the need for new therapies. We show that the histone H3K79 methyltransferase disruptor of [....] » Read More
Title : Outlining the synergistic effects of combining Metformin and Simvastatin in ovarian cancer cells
Sara Mikhael, Saint-Joseph University, Lebanon
Improving response rates in Ovarian cancer is an urgent clinical issue. Drug repurposing offers a safe and a relatively fast alternative to the conventional methods for oncological drug discovery. Both, metformin, a biguanide approved to treat diabetes, and simvastatin, an HMG-Co [....] » Read More
Title : Polymorphism in Thymidylate Synthase gene predicts survival and toxicity in North Indian lung cancer patients undergoing platinum-based doublet chemotherapy
Parul Sharma, Thapar Institute of Engineering and Technology, India
Lung cancer is one of the most widely reported tumors having high morbidity and mortality rates with an estimated 1.8 million fatalities. Thymidylate synthase (TS) is an important target for chemotherapy treatments and platinum-based therapies since it is the cell's only de n [....] » Read More
Title : BIOBRAN MGN-3; Effect of reducing side effects of chemotherapy in breast cancer patients
Dan Kenner, ImunoBran Luxembourg and France, France
The aim of study was to assess the effect of Biobran in reducing of chemotherapy induced side effects in terms of tiredness, anorexia, vomiting and hair loss and quality of life in terms of weight loss. Setting: Radiotherapy Department, Nishtar Hospital Multan. Material and Meth [....] » Read More
Title : Identification of gene-specific signatures associated with AGR2 expression and TGF-? exposure in Lung Cancer cellular model
Andrea Martisova, Masaryk University, Czech Republic
Epithelial to mesenchymal transition (EMT) is one of the key processes in tumour progression and metastasis development. TGF-β signaling plays an important role in this process, and through a cascade of signaling events, it enhances the transcription of EMT drivers. Recently [....] » Read More
Title : Jak 2 negative Polycythemia vera in tertiary care center in west up population in India : A rare presentation of 3 cases
Neema Tiwari, PGICH, Noida, India
Polycythaemia vera (PV) belongs to the group of myeloproliferative neoplasms with excessive increase in hemoglobin levels. They are clinically characterized by nonspecific symptoms such as fatigability, pruritus, early satiety due to splenomegaly, increased risk of infections, an [....] » Read More
Title : The direct and indirect effects of affluence on survival in colon cancer : A population-Based study
Rosie Dew, University of Sunderland, United Kingdom
Background: Colorectal cancer is the fourth most common cancer in the UK. Socio-economic disparities are apparent in colorectal cancer survival in the UK and elsewhere. However, it is not known whether socio-economic status has a direct influence on survival or whether it o [....] » Read More