Gallbladder cancer is a rare but serious malignancy that originates in the gallbladder, a small organ beneath the liver. Typically, this type of cancer is diagnosed at an advanced stage, making treatment challenging. The gallbladder's primary function is to store bile, a digestive fluid produced by the liver. Unfortunately, symptoms of gallbladder cancer often do not manifest until the disease has progressed. Risk factors for gallbladder cancer include age, with the majority of cases occurring in individuals over 70. Additionally, women are more susceptible than men, and certain ethnic groups, such as Native Americans and Mexican Americans, have a higher incidence. Symptoms may include abdominal pain, jaundice, unexplained weight loss, and changes in bowel habits. Due to the nonspecific nature of these symptoms, gallbladder cancer is often diagnosed late in its development. Treatment options for gallbladder cancer may involve surgery, chemotherapy, and radiation therapy. However, the effectiveness of these treatments depends on the stage at which the cancer is detected. Early diagnosis is crucial for better outcomes. Prevention strategies include maintaining a healthy lifestyle, managing risk factors, and seeking medical attention promptly if experiencing symptoms associated with gallbladder issues. As with any cancer, awareness, early detection, and advances in medical research play vital roles in improving the prognosis and quality of life for individuals affected by gallbladder cancer.