Gastric cancer, also known as stomach cancer, originates in the cells lining the stomach. It is a relatively common malignancy, but its incidence varies geographically, with higher rates in certain regions of the world. Gastric cancer often develops slowly over many years, typically starting in the innermost layer of the stomach lining and then spreading to the outer layers as it progresses.
There are several risk factors associated with gastric cancer, including infection with Helicobacter pylori bacteria, a history of certain stomach conditions, smoking, a family history of gastric cancer, and certain genetic factors. Additionally, a diet high in salted, smoked, or pickled foods and low in fruits and vegetables may contribute to an increased risk.
Symptoms of gastric cancer may include indigestion, abdominal discomfort or pain, unintentional weight loss, nausea, and vomiting. However, these symptoms are not specific to gastric cancer and may also be caused by other conditions. The treatment for gastric cancer depends on the stage at which it is diagnosed but often involves surgery to remove the tumor, chemotherapy, and in some cases, radiation therapy. Early detection is challenging, and prognosis is often less favorable for advanced-stage disease. Preventive measures for gastric cancer include addressing modifiable risk factors, such as adopting a healthy diet rich in fruits and vegetables, treating H. pylori infections promptly, and avoiding tobacco use. Ongoing research aims to improve early detection methods and develop more effective treatment strategies for gastric cancer.