Parathyroid cancer is an exceedingly rare form of cancer that originates in the parathyroid glands, which are small glands located near the thyroid gland in the neck. While parathyroid tumors are generally benign, occasionally they can become cancerous, leading to the development of parathyroid cancer. The exact cause of parathyroid cancer remains unclear, and risk factors for its occurrence are not well-defined. Symptoms often overlap with those of hyperparathyroidism, a condition characterized by excessive production of parathyroid hormone. These symptoms may include fatigue, weakness, bone pain, and increased susceptibility to fractures due to elevated calcium levels in the blood. Diagnosing parathyroid cancer can be challenging, as it closely mimics the presentation of benign parathyroid tumors. Confirmation typically involves a combination of imaging studies, blood tests, and a biopsy. Surgical removal of the affected parathyroid gland or glands is the primary treatment for parathyroid cancer. Due to its rarity, there is limited information available regarding the long-term prognosis and optimal treatment approaches for parathyroid cancer. However, early detection and intervention are crucial for improving outcomes. Patients diagnosed with parathyroid cancer may require ongoing monitoring and management to address potential complications associated with elevated calcium levels. In conclusion, parathyroid cancer is an uncommon malignancy arising from the parathyroid glands. While it shares symptoms with benign parathyroid tumors, its rarity and unique characteristics necessitate careful diagnosis and tailored treatment strategies for affected individuals.