Renal biopsy is a medical procedure that involves the extraction of a small tissue sample from the kidney for diagnostic purposes. Typically performed to investigate and identify the underlying causes of kidney disorders, renal biopsy plays a crucial role in guiding appropriate treatment plans. During the procedure, a thin, specialized needle is inserted into the kidney to obtain a small tissue sample. This sample is then examined under a microscope by a pathologist to analyze the structure, composition, and any abnormalities present in the kidney tissue. Renal biopsy is often recommended when other diagnostic methods, such as blood tests or imaging studies, fail to provide a conclusive diagnosis. The information obtained from a renal biopsy is valuable in determining the specific type of kidney disease or injury, which is essential for tailoring an effective treatment approach. Common indications for renal biopsy include chronic kidney disease, glomerulonephritis, nephrotic syndrome, and unexplained proteinuria or hematuria. Although renal biopsy is generally considered a safe and well-tolerated procedure, it is not without risks. Potential complications may include bleeding, infection, or injury to nearby structures. Therefore, careful patient selection and close monitoring during and after the procedure are essential to minimize risks. After the biopsy, patients are typically observed for a short period to ensure there are no immediate complications. Results from the renal biopsy contribute significantly to the development of a precise diagnosis, allowing healthcare professionals to formulate targeted treatment plans and improve patient outcomes in cases of kidney disorders.