Vulvar cancer is a rare but serious form of cancer that affects the external female genitalia, specifically the vulva. The vulva includes the outer and inner lips (labia majora and labia minora), the clitoris, and the opening of the vagina. This type of cancer typically develops slowly over several years, with precancerous changes known as vulvar intraepithelial neoplasia (VIN) preceding the development of invasive cancer. The exact cause of vulvar cancer is not fully understood, but certain risk factors may increase the likelihood of its occurrence. These include age, with the majority of cases diagnosed in older women; persistent human papillomavirus (HPV) infection; smoking; a weakened immune system; and certain skin conditions affecting the vulva. Symptoms of vulvar cancer may include itching, pain, tenderness, or changes in the color or thickness of the skin on the vulva. Women should promptly report any unusual symptoms or changes to their healthcare provider for further evaluation. Treatment options for vulvar cancer depend on the stage of the disease and may include surgery, radiation therapy, chemotherapy, or a combination of these modalities. The choice of treatment is personalized based on the individual's specific case, and healthcare providers work closely with patients to develop a comprehensive and effective treatment plan. Regular gynecological exams and screenings can help detect vulvar cancer at an early stage, improving the chances of successful treatment. HPV vaccination, lifestyle modifications such as smoking cessation, and practicing safe sex can also contribute to reducing the risk of developing vulvar cancer. Overall, early detection and advances in medical treatments have improved the prognosis for individuals diagnosed with vulvar cancer. As with any cancer, a multidisciplinary approach involving oncologists, surgeons, and other healthcare professionals is crucial to providing comprehensive care and support to those affected by this condition.