Understanding how living systems repair and renew themselves underpins much of modern tissue engineering. Biological models of regeneration examine how species such as salamanders, zebrafish, and planarians naturally regrow limbs, spinal tissue, or entire organs. These models reveal key molecular pathways—such as Wnt, BMP, and FGF signaling—that are conserved across species and can be manipulated in human cells for therapeutic purposes. By studying cellular plasticity, immune modulation, and scaffold-independent regeneration, researchers identify principles applicable to human healing. Biological models of regeneration inform the design of synthetic systems, gene circuits, and scaffold-free regeneration strategies, bringing biologically inspired insights into clinical frameworks and strengthening the foundation for transformative therapies.
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Will be updated soon...
Vasiliki E Kalodimou, European University-Cyprus Ltd, Cyprus
Title : Will be updated soon...
Nagy Habib, Imperial College London, United Kingdom
Title : Will be updated soon...
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, United Kingdom
Title : Advanced 3D tissue models: Pioneering tools for investigating health and disease
Lucie Bacakova, Institute of Physiology of the Czech Academy of Sciences, Czech Republic
Title : Developing iPSC-derived 3D Outer Blood-Retinal Barrier Disease Models of Choroideremia for Gene Therapy Evaluation
Aradhana Kasimsetty, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), United States