Understanding how living systems repair and renew themselves underpins much of modern tissue engineering. Biological models of regeneration examine how species such as salamanders, zebrafish, and planarians naturally regrow limbs, spinal tissue, or entire organs. These models reveal key molecular pathways—such as Wnt, BMP, and FGF signaling—that are conserved across species and can be manipulated in human cells for therapeutic purposes. By studying cellular plasticity, immune modulation, and scaffold-independent regeneration, researchers identify principles applicable to human healing. Biological models of regeneration inform the design of synthetic systems, gene circuits, and scaffold-free regeneration strategies, bringing biologically inspired insights into clinical frameworks and strengthening the foundation for transformative therapies.
Title : Eliminating implants infections with nanomedicine: Human results
Thomas J Webster, Interstellar Therapeutics, United States
Title : Biodistribution and gene targeting in regenerative medicine
Nagy Habib, Imperial College London, United Kingdom
Title : Graphene, butterfly structures, and stem cells: A revolution in surgical implants
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, London NW1 0NH, United Kingdom
Title : Precision in cartilage repair: Breakthroughs in biofabrication process optimization
Pedro Morouco, Polytechnic of Leiria, Portugal
Title : Keratin-TMAO wound dressing promote tissue recovery in diabetic rats via activation of M2 macrophages
Marek Konop, Medical University of Warsaw, Poland
Title : Assessing geometric simplifications in vertebral modeling for reliable numerical analysis of intervertebral discs
Oleg Ardatov, Vilnius University, Lithuania