Understanding cellular behavior at the molecular and systemic levels is crucial for advancing tissue-based therapeutics. Cell biology and stem cell engineering together explore how cells function, differentiate, and communicate, with the goal of manipulating these pathways for therapeutic gain. Innovations in reprogramming somatic cells into pluripotent states and engineering them to exhibit specific phenotypes are redefining regenerative interventions. Researchers are applying gene-editing techniques like CRISPR, optimizing signaling pathways, and tuning mechanical environments to guide differentiation into specialized cell types. The combination of bioengineering platforms and advanced imaging techniques allows for real-time tracking of engineered cells in complex environments. As challenges such as immune rejection and tumorigenicity are addressed, cell biology and stem cell engineering are moving closer to creating stable, safe, and scalable solutions. These advancements hold immense potential for treating neurological disorders, musculoskeletal injuries, and metabolic conditions by targeting cellular mechanisms directly.
Title : The era of artificial intelligence (AI) and its use in regenerative medicine
Vasiliki E Kalodimou, European University-Cyprus Ltd, Cyprus
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Stem cells for human disease modelling and potential for tissue repair
Patrizia Ferretti, UCL Great Ormond Street Institute of Child Health, United Kingdom
Title : Advanced 3D tissue models: Pioneering tools for investigating health and disease
Lucie Bacakova, Institute of Physiology of the Czech Academy of Sciences, Czech Republic
Title : The role of gingival fibroblasts in periodontal diseases and regeneration
Katarzyna Gawron, Medical University of Silesia in Katowice, Poland
Title : Personalized and Precision Medicine (PPM): A unique healthcare model via pathology-related modelling and bi-odesign-inspired translational applications for the next gen-eration of human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation