Miniaturized biological systems capable of mimicking complex organ architecture are transforming regenerative medicine. Organoids and lab-grown organs offer powerful platforms for modeling disease, studying development, and exploring therapeutic interventions without relying on animal models. Derived from stem cells and grown in three-dimensional culture systems, organoids self-organize into structures resembling the functional units of organs like the liver, intestine, brain, or kidneys. Coupled with bioreactors and advanced scaffolds, lab-grown organs are progressing toward clinical relevance, especially in transplantation and toxicity testing. Organoids and lab-grown organs bridge developmental biology with engineering, opening new frontiers for personalized treatment, functional organ replacement, and ethical drug discovery that mirrors in vivo responses with remarkable fidelity.
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Will be updated soon...
Vasiliki E Kalodimou, European University-Cyprus Ltd, Cyprus
Title : Will be updated soon...
Nagy Habib, Imperial College London, United Kingdom
Title : Will be updated soon...
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, United Kingdom
Title : Advanced 3D tissue models: Pioneering tools for investigating health and disease
Lucie Bacakova, Institute of Physiology of the Czech Academy of Sciences, Czech Republic
Title : Developing iPSC-derived 3D Outer Blood-Retinal Barrier Disease Models of Choroideremia for Gene Therapy Evaluation
Aradhana Kasimsetty, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), United States