Miniaturized biological systems capable of mimicking complex organ architecture are transforming regenerative medicine. Organoids and lab-grown organs offer powerful platforms for modeling disease, studying development, and exploring therapeutic interventions without relying on animal models. Derived from stem cells and grown in three-dimensional culture systems, organoids self-organize into structures resembling the functional units of organs like the liver, intestine, brain, or kidneys. Coupled with bioreactors and advanced scaffolds, lab-grown organs are progressing toward clinical relevance, especially in transplantation and toxicity testing. Organoids and lab-grown organs bridge developmental biology with engineering, opening new frontiers for personalized treatment, functional organ replacement, and ethical drug discovery that mirrors in vivo responses with remarkable fidelity.
Title : The era of artificial intelligence (AI) and its use in regenerative medicine
Vasiliki E Kalodimou, European University-Cyprus Ltd, Cyprus
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Stem cells for human disease modelling and potential for tissue repair
Patrizia Ferretti, UCL Great Ormond Street Institute of Child Health, United Kingdom
Title : Advanced 3D tissue models: Pioneering tools for investigating health and disease
Lucie Bacakova, Institute of Physiology of the Czech Academy of Sciences, Czech Republic
Title : The role of gingival fibroblasts in periodontal diseases and regeneration
Katarzyna Gawron, Medical University of Silesia in Katowice, Poland
Title : Personalized and Precision Medicine (PPM): A unique healthcare model via pathology-related modelling and bi-odesign-inspired translational applications for the next gen-eration of human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation