A substantial number of lesions in soft tissue pathology requires diagnostic precision for adequate patient care management and follow-up. Also, margin status of surgical specimens must be unequivocally defined, preferably intra-operatively, because of the tight relation which ex [....] » Read More
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As it is obvious, nowadays cancer is one of the most common disorders all around the world and nobody can ignore the importance of getting educated about them, types, how they spread around the body and how they can be treated and also some procedures after treatment because ever [....] » Read More
Small-molecule based probes have been used to tag biomolecules site-selectively on molecular basis to enhance diagnostic approaches in cancer. We designed a small molecule-based probe which incorporated with the carbonyl moiety of biomolecules through a click reaction to form a f [....] » Read More
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Technological advancements and recent discoveries in cancer therapy have decreased cancer-related mortality. But the principal objective of improving quality of life through advanced cancer treatments is compromised by poor management of pain (especially Neuropathic Pain (NP)) in [....] » Read More
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Technological advancements and recent discoveries in cancer therapy have decreased cancer-related mortality. But the principal objective of improving quality of life through advanced cancer treatments is compromised by poor management of pain (especially Neuropathic Pain (NP)) in [....] » Read More
Will be Updated Soon...
Hepatocellular Carcinoma (HCC), a primary type of liver cancer, remains one of the deadliest malignancies worldwide. Despite decades of targeted therapy advancements, the currently approved medications for advanced HCC provide patients with limited clinical benefits. One major ob [....] » Read More
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Title : Point-of-care Tool for Early Diagnosis of Ovarian Cancer
Michael Thompson, University of Toronto, Canada
High grade serous ovarian cancer (HGSOC) histologic subtypes make up the majority of epithelial ovarian cancer and 85% of cases are diagnosed at advanced stages, in which the 5-year relative survival could be as low as 20%. Unfortunately, only 20% of patients are diagnosed at sta [....] » Read More
Title : Clinical trial evaluating the efficacy of systemic mesenchymal stromal cell injections for the treatment of severe and chronic radiotherapy-induced abdomino-pelvic complications refractory to standard therapy
Alain Chapel, Institute Of Radiological Protection And Nuclear Safety, France
The late adverse effects of pelvic radiotherapy concern 5 to 10% of patients, which could be life threatening. However, a clear medical consensus concerning the clinical management of such healthy tissue sequelae does not exist. Our group has demonstrated in preclinical animal mo [....] » Read More
Title : Role of Membrane Cholesterol in Breast Cancer Cell Invasion
Mauriane Maja, de Duve Institute, UCLouvain, Belgium
Breast cancer mortality is almost exclusively due to metastatic disease. Better molecular characterization of the primary tumor is therefore crucial for a good prediction of the clinical outcome. Breast cancer cells are characterized by aberrant lipid accumulation and metabolism. [....] » Read More
Title : Identification of Key Pathological Features Associated with Melanoma Survival by Artificial Intelligence NLP
Anna Lian, Brigham and Women’s Hospital/Harvard Medical School, United States
Immunotherapy has reshaped the landscape of cancer treatment, showing promising treatment responses in melanoma. Currently, there are no pathological features which consistently predict treatment responses in melanoma; existing studies have involved small cohorts and shown confli [....] » Read More
Title : Purification and characterisation of lectin isolated from Nigeria Achatina achatina Snail
Odiegwu Chukwujekwu Nwabueze C, Nnamdi Azikiwe University-Nnewi Campus, Nigeria
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Title : A novel mechanism that promotes mitotic spindle formation in cancer cells
Eleni Petsalaki, University of Crete, Greece
During cell division, the mitotic spindle consists mainly of microtubules (MTs) and is essential for accurate distribution of the genetic material to the two daughter cells. Errors in spindle formation can lead to incorrect separation of chromosomes that is associated with tumori [....] » Read More
Title : Neuropsychology of breast cancer patients
Kalliopi Megari, Aristotle University of Thessaloniki, Greece
Post chemotherapy cognitive impairment (PCCI), is referred to a decrease in neuropsychological performance of neurocognitive measures after chemotherapy for the treatment of cancer. Chemotherapeutic drugs are often affecting both normal and cancer cells and the cause of cognitive [....] » Read More
Title : Entosis in cancer: Death or survival?
Izabela Mlynarczuk Bialy, Medical University of Warsaw, Poland
The process of entosis is not widely known phenomenon, that can impact diagnosis and prognosis of cancer. The phenomenon is characterized by the active invasion of one cell into another and the formation of “cell in cell structures” (CIC), with the participation of Rh [....] » Read More
Title : Can prostate cancer originate in utero? Prostate carcinogenesis induced by maternal low protein diet in older offspring
Sergio Alexandre Alcantara Dos Santos, Sao Paulo State University UNESP, Brazil
Although the carcinogenesis is frequently linked to genetic background, exposure to environmental risk factors has gained attention as the etiologic agent for several types of cancer. The intrauterine microenvironment has been described as preponderant factor for offspring health [....] » Read More
Title : AIDS related Kaposi sarcoma in Brazil
Ana Luiza de Castro Conde Toscano, Emilio Ribas Infectious Diseases Institute, Brazil
Kaposi's sarcoma (KS) is a mesenchymal tumor, caused by herpes virus type 8 (HHV-8), and a characteristic neoplasm of acquired immunodeficiency syndrome (AIDS). After the emergence of AIDS in 1980, a more aggressive form of the disease, more common among homosexual or bisexua [....] » Read More
Title : Genome-wide comparative analysis of long non-coding RNAs versus protein-coding transcripts reveals distinct expression profiles and patient survival correlations across cancer types
Paola Marcato, Dalhousie University, Canada
Long non-coding RNAs (lncRNAs) are emerging targets for the diagnosis and therapeutic treatment of cancer. LncRNAs are non-protein-coding transcripts that regulate gene expression by modulating chromatin structure or by interacting with other RNA species. Additionally, they exhib [....] » Read More
Title : Increased viral richness in colorectal cancer tissues
Luigi Marongiu, University of Heidelberg, Germany
Colorectal cancer (CRC) is a major burden for the Public Health worldwide. It has been proposed that CRC has an infectious aetiology but no statistical association has been observed between disease and microbial species. On the other hand, modification of the relative prevalence [....] » Read More
Title : KLF7 promotes pancreatic cancer growth and metastasis by up - Regulating ISG expression and maintaining Golgi complex integrity
Romi Gupta, University of Alabama, United States
Pancreatic ductal adenocarcinoma (PDAC) is the fourth- leading cause of cancer-related deaths in the United States and is expected to become the second-leading cause by 2020. The five-year disease-free survival rate for patients with PDAC is extremely low and has remained <10% [....] » Read More
Title : The role of EMT in angiogenesis-mediated tumor progression
Tapasree Roy Sarkar, Texas A&M University, United States
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Title : Fatty acid-like Pt(IV) prodrugs overcome cisplatin resistance in ovarian cancer by harnessing CD36
Amarasooriya M D S Jayawardhana, Kent State University, United States
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Title : Delaying the final cut: An ATM-Chk2-INCENP pathway prevents chromatin bridge breakage in cytokinesis
George Zachos, University of Crete, Greece
Chromatin bridges are strands of missegregated chromatin connecting the anaphase poles or daughter nuclei and have been linked to tumourigenesis. In response to chromatin bridges in cytokinesis, cells delay abscission, the severing of the narrow cytoplasmic canal that connects th [....] » Read More
Title : Oncologic patients have mutual relations of nosological form of the first tumour and second cancers
Yevheniia Radzishevska, Kharkiv National Medical University, Ukraine
The aim of presentstion will to demonsrate the relationship between nosological forms of the primary and second neoplasms in patients who have undergone special treatment for cancer, and who have developed second neoplasms three and more years after the end of treatment. It [....] » Read More