Vibrational optical coherence tomography (VOCT) is a new technique to optically image and measure the resonant frequency of cells, blood vessels, papillary collagen, and fibrotic tissue in the skin and other soft tissues. The technique uses low levels of infrared light (0.1mW) fo [....] » Read More
A case of about-80-year-old-female is herein presented. She felt palpable mass in her right breast of about 10mm-in-diameter before 1 year for our exams. In this time, she felt the mass is larger and larger. Hence, she came to our hospital for further examinations and treatments. [....] » Read More
Introduction: Photodynamic therapy (PDT) had been used for benign and malignant skin lesions for some time. It can disinfect caries dentin before restoration or oral tissues before or during surgical procedures, treat denture stomatitis, and oral candidiasis in immunocompromised [....] » Read More
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Introduction/Purpose: The mortality rate of cancer patients has been decreasing; however, patients often suffer from cardiac disorders due to chemotherapy or other cancer therapies (e.g., cancer therapy-related cardiovascular toxicity, CVR-CVT). Therefore, the field of cardio-onc [....] » Read More
Introduction: Oral cancer ranks as the sixth most commonly diagnosed cancer type originating from oral tissues. The incidence of oral cancer varies globally, with higher prevalence in developing countries. Traditional risk factors such as tobacco, alcohol, and Human Papilloma Vir [....] » Read More
Chromatin bridges are strands of incompletely segregated DNA connecting the anaphase poles or daughter nuclei. Chromatin bridges can arise from incompletely replicated DNA, defective resolution of DNA catenates or dicentric chromosomes which are formed by chromosome fusions. If u [....] » Read More
Breast cancer is the most common malignancy in women worldwide and remains a leading cause of câncer related mortality. While the immune system plays key role in controlling tumor progression, it is often suppressed in breast cancer. Dendritic cells (DCs), which connect inn [....] » Read More
Background: Little is known of the synergy of combination intratumoral immunotherapy and cancer ablation. We undertook a Phase II Trial (Abscopal 5001; NCT04713371) for patients with metastatic solid cancer to assess the safety and efficacy of cryoablation with concurrent injecti [....] » Read More
To stop cancer development the prime target would be intercept of electro-gravitational impulses(0.0107 or 0.0106 unit) entering into the cell system. A difference of 0.0001(1) is natural in directional biology. I shall determine the interplay of lunar time(183 or 0.3477 or 777), [....] » Read More
Background: The prognostic value of neoadjuvant therapy (NAT) in patients with gastric linitis plastica (GLP) remained controversial. This study aimed to analyze the effect of NAT therapy on short- and long-term patients with GLP. Methods: This multi-center study enrolled pati [....] » Read More
Aim: This study delves into cutting-edge cancer treatments by leveraging advancements in quantum biology, genomics, and artificial intelligence. Additionally, it investigates the integration of AI- generated auto-contours, using deep learning segmentation, into diverse treatment [....] » Read More
Breast cancer remains one of the most prevalent and life-threatening diseases, with early detection playing a crucial role in improving patient outcomes. Deep learning techniques have emerged as powerful tools for automating cancer diagnosis, yet challenges persist in optimizing [....] » Read More
Lung cancer is among the most fatal cancers, necessitating advanced diagnostic tools for early detection. This study investigates the performance of a novel deep learning approach combining EfficientNet with an attention-based Transformer model to classify lung cancer images from [....] » Read More
Introdcution: In-transit metastases (ITM) in melanoma is a type of locoregional metastasis found between the primary tumour site and the regional draining lymph node. Treating ITM can be a challenge; some recur after surgery alone and others are unresectable at presentation. Immu [....] » Read More
The sensible improvement of anticancerous specialists that explicitly target threatening malignant cells without impacting the normal cells or tissues, has provoked the use of microbe assisted bioactive substances. Such fundamental discovery could get ready to beat the shortcomin [....] » Read More
Colon cancer remains one of the most elusive cancers to detect, as it often shows no symptoms in its early stages. Additionally, its gold-standard diagnostics carry substantial risks, while existing cancer detection studies are narrowly focused on the microscopic scale, leaving a [....] » Read More
Title : Gene activation and delivery
Nagy Habib, Imperial College London, United Kingdom
For over three decades Nagy has been at the forefront of clinical research and clinical practice in cancer. He pioneered the first clinical trial in the use of adenovirus and plasmid for the treatment of liver cancer, as well as the use of plasmid gene therapy in hydrodynamic gen [....] » Read More
Title : Innovative diagnostic tool in sarcomas with mass spectrometry
Yves Marie Robin, Oscar Lambret Cancer Center, France
Classification of soft tissue tumors is expanding to include new entities of which the ermeging ones are sometimes described solely by their molecular recurrent characteristics. Diagnostic tools development are also on the rise with « multi-omics » systems d [....] » Read More
Title : Targeting the post-translationally generated epitopes to fight cancer
Michele Mishto, The Francis Crick Institute, United Kingdom
MHC class I complexes can present antigenic peptides that have a sequence produced by post-translational mechanisms such as peptide splicing. Some examples of tumour-associated spliced epitopes have been investigated for their immunogenicity in the context of cancer so far. We de [....] » Read More
Title : Serum based machine learning models to assess the risk of liver cancer
Jianhua Luo, University of Pittsburgh School of Medicine, United States
Hepatocellular carcinoma (HCC) is one of the most lethal malignancies for human. Early diagnosis of HCC is crucial in reducing the mortality of the disease. In this study, a panel of 9 fusion transcripts in the serum samples from 136 individuals using TaqMan qRT-PCR was analyzed. [....] » Read More
Title : Association between occupational classifications and symptom burden in patients with advanced cancer: A multicenter cross-sectional study in China
Mo Tang, Chongqing Cancer Hospital, China
Background: Little is known about the relationship between psychosomatic symptoms and different occupations in patients with advanced cancer. Aim: To assess the prevalence of psychosomatic symptoms and the status of symptom burden management among advanced cancer survivors with d [....] » Read More
Title : Digital symptom management tool use among metropolitan-dwelling older adults with cancer in China: A qualitative exploration of experiences
Jie Ding, Zhejiang Chinese Medical University, China
Introduction: With the rapid advancement of digital health technologies, digital symptom management tools (DSMTs) have emerged as promising interventions to support self-management of cancer-related symptoms. These tools offer real-time monitoring and personalized feedback, poten [....] » Read More
Title : The role of handgrip strength and functional capacity in predicting health outcomes in adolescents and young adults with cancer: A study from Nigeria
Osueke Anastasia Ngozi , Babcock University, Nigeria
Background: Adolescents and Young Adults (AYAs) with cancer face unique challenges impacting their physical and psychosocial well-being. This study aims to assess hand grip strength, functional capacity, and quality of life among AYAs with cancer at Lagos State University Teachin [....] » Read More
Title : Stage at diagnosis and survival among adult patients with cancer in Rwanda: a population-based study
Marc Hagenimana, Rwanda Biomedical Centre, Rwanda
Background: There are marked disparities in cancer survival between low-income and high-income countries, yet population-based survival data from low-income settings remain scarce. Understanding cancer survival patterns is crucial for guiding cancer control strategies and improvi [....] » Read More
Title : Defining innate immune cell mechanisms upon Helicobacter pylori mediated tumorigenesis
Tyanna Supreme, The Hospital for Sick Children, Canada
Gastric cancer is one of the most common and deadliest cancers in the world. Patients face a 25% five-year survival rate and diagnosis is often delayed as gastric cancer typically presents as asymptomatic or with nonspecific symptoms2. There are many environmental, epigenetic, an [....] » Read More
Title : The impact of social marketing based intervention on educating esophageal cancer preventive behaviors
Davoud Shojaeizadeh, Tehran University of Medical Sciences, Iran (Islamic Republic of)
Esophageal cancer is one of the most widespread disease in Golestan Province , Iran. To identify risk factors a lot of research has been done. Because health workers have successful experiences of health education. The purpose of this study is to use social marketing to influence [....] » Read More
Title : A need for innovation to detect and prevent perineural invasion
Emma Turner, Johns Hopkins University, United States
Perineural invasion (PNI) in head and neck cancer (HNC) is a critical factor associated with poor prognosis, increased recurrence, metastasis, and reduced survival rates [1,2]. PNI occurs when cancer cells invade the perineural space surrounding nerves, allowing tumor spread thro [....] » Read More