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International Summit on Hematology and Blood Disorders

April 27-29, 2023 | Orlando, USA

April 27 -29, 2023 | Orlando, Florida, USA
Hematology 2023

The utility of SYNTAX score predictability by electrocardiogram parameters in patients with unstable angina

Hamed Bazrafshan, Speaker at Hematology Conferences
Shiraz University of Medical Sciences, Iran (Islamic Republic of)
Title : The utility of SYNTAX score predictability by electrocardiogram parameters in patients with unstable angina

Abstract:

Abstract: Background: SYNTAX score is one of the risk assessment systems to predict cardiac events in acute coronary syndrome patients. Despite the large number of SYNTAX score benefits, invasive methods such as coronary angiography are necessary to perform the scoring. We hypothesized that ECG parameters could predict the SYNTAX score in unstable angina patients.
Methods: During the retrospective cohort study, a total number of 876 patients were diagnosed with unstable angina. After applying the exclusion criteria, 600 patients were divided into tertiles based on the SYNTAX scores as low (0–22), intermediate (23–32), and high (≥ 33). The association between ECG parameters and SYNTAX score was investigated.
Results: The study included 65% men and 35% women with a mean age of 62.4 ± 9.97 years. The delayed transition zone of QRS complex, ST-depression in inferior-lateral territories or/and in all three territories, and T-wave inversion in lateral territory were significant (p < 0.05) independent predictors of intermediate SYNTAX score. High SYNTAX score was predicted by the presence of prolonged P wave duration, ST-depression in lateral territory or/and anterior-lateral territories, ST-elevation in aVR–III leads or/and aVR–III–V1 leads. Among those, all three territories ST-depression (AUC: 0.611, sensitivity: 75%, specificity: 51%) and aVR + III ST-elevation (AUC: 0.672, sensitivity: 50.12%, specificity: 80.50%) were the most accurate parameters to predict intermediate and high SYNTAX scores, respectively.
Conclusion: The present study demonstrates that accompanying the STE in the right side leads (aVR, III, V1) with ST-depression in other leads indicates the patients with high SYNTAX score; meanwhile, diffuse ST-depression without ST-elevation is a marker for intermediate SYNTAX score in unstable angina patients and can be applied for early risk stratification and intervention.
What will audience learn from your presentation?

  • Explain how the audience will be able to use what they learn?

Decision-making about choosing the proper modality for the revascularization between the percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) was facilitated by the SYNTAX score. With the increase in CAD patients who underwent revascularization, the demand for risk stratification to predict the outcome was felt. We hypothesized that ECG parameters could predict the SYNTAX score in unstable angina patients.

  • How will this help the audience in their job? Is this research that other faculty could use to expand their research or teaching? Does this provide a practical solution to a problem that could simplify or make a designer’s job more efficient? Will it improve the accuracy of a design, or provide new information to assist in a design problem? List all other benefits.

Recognizing the patients with severe CAD or intermediate and high SYNTAX scores using non-invasive tools are extremely helpful, especially for centers without advanced facilities. ECG can be used for this purpose. The present study demonstrates that accompanying the STE in the right side leads (aVR, III, V1) with STD in other leads indicates the patients with high SYNTAX score; meanwhile, diffuse depression of ST-segment without STE is a marker for intermediate SYNTAX score. These predictors aid us in early risk stratification and intervention.

 

Biography:

Dedicated and caring cardiologist with more than 4 years’ experience in clinical practice, helping over 70 patients (inpatient and outpatient) with their cardiac ailments on a daily basis.
Conducting research on cardiovascular disease and treating patients accordingly.
Working as attending at Shiraz University of Medical Science for 4 years and teaching medical students and residents of cardiology.
Proficiency in teaching clinical cardiology and serve as a problem based learning (PBL) tutor at various stages in the medical program (The best attending of shiraz medical university at education).

 

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