Lifeng Yang

Title : Pulsed photoacoustic non-invassive glucose measurement based on dual-wavelength near infrared differential-absorption method

Abstract:

Non-invasive, portable, economical, dynamic blood glucose monitoring device has become a functional requirement for diabetes in his regulating entire life. In photoacoustic (PA) dual-wavelength near infrared differential-absorption measurement, the glucose in aqueous solutions was excited by two short duration (order of nanoseconds) diode laser pulse system which wavelengths were 1560nm and 1392nm, respectively. The glucose in aqueous solutions to be analyzed was contained within the first photoacoustic cell (PAC), whereas the presence of a second reference photoacoustic cell (PAC) provided energy monitoring.

The PA pulsed signals were measured using a piezoelectric detector and the voltage pulses from the piezoelectric detector were amplified with a precision AC 9452 amplifier, the PA signal strength (PSS) was computed as the integration of the Hilbert Transform of the PA signal. To investigate the possible contributions of other blood analytes to the total photoacoustic response from blood, solutions of sodium chloride, cholesterol, and Bovine Serum Albumin (BSA) were investigated. The function generation and signal acquisition were performed in the PC using Labview software.

The experimental results showed that the photoacoustic (PA) dual-wavelength near infrared differential-absorption measurement can be engineered to detect blood glucose. The results of our study have the potential to not only better develop photoacoustic (PA) blood glucose meter, but also extend the viability and use of photoacoustics into detection of otherwise blood components.

What will audience learn from your presentation?

• Give biomedical photonics researchers a good understanding of photoacoustic detection.
• Dual wavelength differential photoacoustic detection for non-invasive blood glucose technology in this work can be used in real life
• Improve the range and accuracy of dual-wavelength differential photoacoustics.

Biography:

Dr. Lifeng Yang received his BS degree in physics from the University of Electronic Science and Technology of China (UESTC), Chengdu,China, in 2003. He received his MA  degree in 2006 and PhD in 2012 in optical engineering from UESTC. Between February 2013 and February 2014, he was a visiting scholar in the Center for Advanced Diffusion- Wave Technologies (CADIFT), University of Toronto, Canada, for research in biomedicalphotoacoustic imaging. He obtained the position of an Associate Professor  from 2016 at the UESTC. He has published more than 20 research articles in SCI(E) journals.