Animal model system research has aided in the discovery of better treatments for breast cancer. There are now a plethora of models available that reflect various types and stages of disease; which one to utilise depends on the specific research question(s) to be investigated. Due to their particular near-infrared laser absorption, gold nanorods are excellent photothermal agents in the treatment of breast cancer. However, tumor laser photothermal treatment with nanorods alone is ineffective since it is not targeted. Poly(vinylpyrrolidone) (PVP) has developed a new seedless manufacturing method for gold nanorods (AuNRs). Gold NPs with a PVP surface modification decreased endothelial cell (EC) viability and proliferation.
Keywords: Breast cancer , Gold nanoparticles, PDT, , Rat, laser
Walid Tawfik, is an Egyptian Professor, in laser physics, laser spectroscopy and ultrafast lasers at the National Institute of Laser (NILES), Cairo University, Cairo, Egypt. In 1994 he joined NILES as staff member and promoted as assistant lecturer, assistant professor, associate Professor and full professor in 1996, 2000, 2008 and, 2017 respectively. He received the B.SC, Master and Ph.D degrees in physics, laser physics, and laser spectroscopy in 1992, 1996, 2000, respectively, from Cairo University, Egypt. His interested in the field of ultrafast lasers and ultrafast phenomenon. His research plans are devoted to ultrafast optics and photonics: nonlinear interactions of short laser light and matter using time-resolved spectroscopy for laser-pulse durations from nanosecond to few-cycle.