Title : Treatment of Breast cancer using laser induced Photodynamic Therapy and Gold Nanoparticles
Abstract:
Animal model system research has aided in the discovery of better treatments for breast cancer. There are now a plethora of models available that reflect various types and stages of disease; which one to utilise depends on the specific research question(s) to be investigated. Due to their particular near-infrared laser absorption, gold nanorods are excellent photothermal agents in the treatment of breast cancer. However, tumor laser photothermal treatment with nanorods alone is ineffective since it is not targeted. Poly(vinylpyrrolidone) (PVP) has developed a new seedless manufacturing method for gold nanorods (AuNRs). Gold NPs with a PVP surface modification decreased endothelial cell (EC) viability and proliferation.
Keywords: Breast cancer , Gold nanoparticles, PDT, , Rat, laser