In Lipogems Treatment, human tendon stem cells (hTSCs) from the rotator cuff were cocultured in a transwell system with the Lipogems lipoaspirate product and compared to control untreated cells in terms of cell proliferation, morphology, somatic cell marker and VEGF expression, and differentiation and migration capabilities. Results showed that Lipogems product remarkably increases the proliferation rate of hTSCs without altering their stemness and differentiation capability.
Adipose tissue stem cells (ASCs), referred to as multipotent stem cells, are most ordinarily utilized in the clinical applications in recent years. Adipose tissues (AT) have the benefit within the harvesting, isolation, and expansion of ASCs, especially an abundant amount of stem cells compared to bone marrow. ASCs are often found in stromal vascular fractions (SVF) which are easily obtained from the dissociation of fat.
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