A physiologically active substance is a chemical that participates in and influences living processes in a minor way. Vitamins and coenzymes, hormones, antibiotics, neurotransmitters, and cytokines are examples of biologically active compounds. They primarily regulate biological functions and are also being investigated as potential medicinal candidates. Bioactive agents can be integrated into polymers, which can be used in medicine delivery, commercial manufacturing of household goods, and biomedical device development. Bioactive compounds are placed into enzyme-responsive polymers in drug delivery systems, which can subsequently be cleaved by target enzymes. The release of therapeutic cargos is triggered by the activation of bioactive substances.
A substance that allows a cell to mature from an immature state to a mature state is known as a differentiation agent. A differentiation agent may help cancer cells grow and spread more slowly by allowing them to become more like normal cells. Differentiating agents are being researched for cancer prevention and treatment.
Title : Small activating RNA from concept to phase 2 clinical trials
Nagy Habib, MiNA Therapeutics Ltd, United Kingdom
Title : Mechanical modulation of cell response in 3D bioprinted hydrogels
Ruben F Pereira, University of Porto, Portugal
Title : Electroactive polymer-based smart scaffolds for tissue engineering and regenerative medicine
Federico Carpi, University of Florence, Italy
Title : Graphene “Hastalex®”, butterfly, and stem cells are set to revolutionise the development of human organs.
Alexander Seifalian, NanoRegMed Ltd, BioScience Innovation Centre, United Kingdom
Title : Design of 3D bioengineered personalized scaffolds to potentiate bone ingrowth and angiogenic network for oral tissues reconstruction
Christiane Salgado , Institute of Research and Innovation in Health(i3S), Brazil
Title : RADA16-I based scaffolds for wound healing and regenerative medicine
Deptula Milena, Medical University of Gdansk, Poland