Despite breakthroughs in interventional, pharmacological, and surgical therapy, organ failure remains the top cause of death worldwide. Since then, beyond human memory, bioartificial organ manufacturing has been a long-term goal. Man-made organs may, in the not-too-distant future, save the lives of people whose kidneys, pancreas, or lungs are failing. The design, modification, growth, and maintenance of living tissues implanted in natural or synthetic scaffolds to enable them to execute complicated biochemical activities, such as adaptive regulation and the replacement of regular living tissues, are all part of bioartificial organs. Healthy human cells (produced from organ tissue discarded during surgery) and biomaterials are used to construct bioartificial organs. A bioartificial kidney, for example, is constructed from kidney cells that have been cleverly linked to a ′membrane, ′ a porous capillary built from artificial polymer fibre. When human plasma is pushed via this tube, it reaches the kidney cells, which detect and eliminate toxins. In vitro, this bioartificial kidney can filter and cleanse blood, simulating the function of a real, healthy kidney. Future research will move away from the trial-and-error approach to implant optimization and toward the rational manufacturing of precisely formed nano biological devices.
Title : Comparison of different nanofiber scaffolds effects on bone regeneration of calvaria defect in a wistar rat model _importance of porosity
Fanny Gimie, Gip Cyrio, France
Title : Efficacy and safety outcomes in patients with chronic traumatic brain injury: final analysis of the randomized, double-blind, surgical sham-controlled phase 2 STEMTRA trial
Bijan Nejadnik, SanBio, Inc, United States
Title : Early and automatic breast cancer detection and screening using thermal imaging
Alamirew Kefale, University of Gondar, Ethiopia
Title : MicroRNAs in the composition of platelet- Rich fibrin
Indre Jasineviciute, Lithuanian University of Health Sciences, Lithuania
Title : A revolution or surrender: The success and failures of tissue engineering and regenerative medicine
Thomas J Webster, Hebei University of Technology, United States
Title : Electroactive polymers as artificial muscle materials: New opportunities for biomaterials and tissue engineering
Federico Carpi, University of Florence, Italy