A Bioreactor can be characterized as a device that uses mechanical means to influence biological processes. In tissue engineering bioreactors can be utilized to aid in the in vitro development of new tissue by providing biochemical and physical regulatory signals to cells and encouraging them to undergo differentiation to produce extracellular matrix prior to in vivo implantation.
Regulation of cell function in tissue engineering
The regulation of cell function and the growth of three dimensional tissues are major areas of focus in developing new tissue engineering techniques. In order to determine design criteria for tissue engineering, For a cell to respond to its environment extracellular signals need to be sensed, reach the nucleus, and then have to trigger the specific expression of particular genes. These extracellular signals can promote or restrain cell proliferation, migration and differentiation, trigger matrix remodelling, or promote enhanced tissue organization.
Title : Small activating RNA from concept to phase 2 clinical trials
Nagy Habib, MiNA Therapeutics Ltd, United Kingdom
Title : Mechanical modulation of cell response in 3D bioprinted hydrogels
Ruben F Pereira, Universidade do Porto, Portugal
Title : Electroactive polymer-based smart scaffolds for tissue engineering and regenerative medicine
Federico Carpi, University of Florence, Italy
Title : Graphene “Hastalex®”, butterfly, and stem cells are set to revolutionise the development of human organs.
Alexander Seifalian, NanoRegMed Ltd, London BioScience Innovation Centre, United Kingdom
Title : Design of 3D bioengineered personalized scaffolds to potentiate bone ingrowth and angiogenic network for oral tissues reconstruction
Christiane Salgado , Instituto de Investigação e Inovação em Saúde (i3S)/Instituto Nacional de Engenharia Biomédica (INEB), Brazil
Title : RADA16-I based scaffolds for wound healing and regenerative medicine
Deptula Milena, Laboratory of Tissue Engineering and Regenerative Medicine, Department of Embryology, Medical University of Gdansk, Poland