Tissue engineering of musculoskeletal tissues, especially bone and cartilage, is a quickly propelling field. In bone, innovation has fixated on bone unite substitute materials and the improvement of biodegradable scaffolds. Tissue engineering methodologies have included cell and gene therapy. The accessibility of development factors and the growing information base concerning the genetics and regulation of bone formation have generated new materials for tissue-engineering applications. The issues are more perplexing, and the solutions appear more elusive. Innovations in scaffold design and cell culture have improved the prognosis for success. A number of matrices have been tested in vitro and in vivo in preclinical and clinical examinations. These networks can be characterized by their nature.
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A C Matin, Stanford University School of Medicine, United States
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Yong Xiao Wang, Albany Medical College, United States
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Patrizia Ferretti, UCL Great Ormond Street Institute of Child Health, United Kingdom
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Federico Carpi, University of Florence, Italy
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