Brown Fat Cells, or brown adipocytes, are a specialized type of adipocyte found in brown adipose tissue (BAT). Unlike white adipocytes, which store energy in the form of triglycerides, brown adipocytes are geared toward thermogenesis—the production of heat. This is primarily facilitated by a high concentration of mitochondria in brown fat cells, containing a unique protein called uncoupling protein 1 (UCP1). UCP1 allows brown fat cells to uncouple oxidative phosphorylation from ATP production, dissipating energy as heat instead. This adaptive mechanism is crucial for maintaining body temperature, especially in infants and hibernating animals. Brown fat cells have garnered significant attention in metabolic research due to their potential role in energy expenditure and weight regulation. While traditionally thought to be more prevalent in infants, recent studies have identified active brown adipose tissue in adult humans. Stimulating brown fat activity, through methods like cold exposure or pharmacological interventions, is being explored as a potential strategy to enhance metabolic health and combat obesity-related disorders. Understanding the physiology and molecular mechanisms of brown fat cells provides valuable insights for developing therapeutic approaches aimed at modulating energy balance and improving overall metabolic function.
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Stem cell technologies to integrate biodesign related tissue engineering within the frame of cell based regenerative medicine: towards the preventive therapeutic and rehabilitative resources and benefits
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : In vitro evaluation of lyophilized Dedifferentiated Fat cells (DFAT) impregnated artificial dermis
Kazutaka Soejima, Nihon University, School of Medicine, Japan
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Nagy Habib, Imperial College London, United Kingdom
Title :
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, United Kingdom
Title : The regenerative medicine of the future
Marco Polettini, DVM, Italy