Langer and Vacanti characterized tissue engineering (TE) in the early 1990s as "an interdisciplinary area that uses engineering and life science ideas to the development of biological substitutes that restore, maintain, or improve tissue function". The goal of TE is to trigger tissue-specific regeneration mechanisms, overcoming the well-known difficulties of organ transplantation (i.e., donor shortage, need of immunosuppressive therapy). Biomaterials are essential in tissue engineering because they allow cells or growth agents to be delivered efficiently. Biomaterials can be used as carriers to transport cells to a desired location and induce local tissue regeneration, as barriers to protect transplanted cells or tissues from host immune response, or as reactors to drive host cell recruitment, homing, and differentiation. An optimal biomaterial for tissue engineering should have a high cell survival rate, proper cell function after transplantation, and the ability to promote autologous functional tissue growth in situ, as well as its own deterioration when therapy is completed.
Title : A revolution or surrender: The success and failures of tissue engineering and regenerative medicine
Thomas J Webster, Hebei University of Technology, China
Title : Open abdomen and negative pressure wound therapy for acute peritonitis especially in the presence of anastomoses and ostomies
Orestis Ioannidis, Aristotle University of Thessaloniki, Greece
Title : RNA activation in cancer and rare genetic diseases
Nagy Habib, Imperial College London, United Kingdom
Title : Light-based bioprinting: From bioink design to modulation of cell response in bioprinted hydrogels
Ruben F Pereira, University of Porto, Portugal
Title : Sandeep’s Procedure for Induction of Neo-angiogenesis (SPIN) for management of necrosis in tissue & impending gangrenes
Sandeep Shrivastava, Datta Meghe Institute of Medical Sciences, India
Title : Novel molecular mechanisms and therapeutic options for pulmonary hypertension
Yong Xiao Wang, Albany Medical College, United States