Cell Rejuvenation, a burgeoning field in biomedical research, focuses on restoring the vitality and functionality of aging or damaged cells. Unlike traditional approaches that merely manage symptoms, cell rejuvenation aims to reverse cellular aging processes and promote cellular repair and regeneration. This involves targeting various aspects of cellular function, including DNA repair mechanisms, mitochondrial health, protein homeostasis, and telomere maintenance, to restore cellular youthfulness and resilience. At the forefront of cell rejuvenation research are interventions that stimulate cellular repair mechanisms and enhance cellular resilience. These interventions may include lifestyle modifications, such as calorie restriction and exercise, which activate cellular stress response pathways like autophagy and promote mitochondrial biogenesis. Additionally, emerging pharmacological interventions and gene therapies are being developed to target specific pathways involved in cellular aging, such as senescence, inflammation, and oxidative stress. Cell rejuvenation strategies also encompass regenerative medicine approaches that aim to replenish aging or damaged tissues with healthy, rejuvenated cells. Stem cell therapies, for instance, involve the transplantation of stem cells or their derivatives to replace dysfunctional or depleted cells and promote tissue regeneration. Similarly, tissue engineering techniques enable the fabrication of artificial tissues or organs using biomaterials and cell-based constructs, offering promising solutions for restoring tissue function and vitality.
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Will be updated soon...
Vasiliki E Kalodimou, European University-Cyprus Ltd, Cyprus
Title : Will be updated soon...
Nagy Habib, Imperial College London, United Kingdom
Title : Will be updated soon...
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, United Kingdom
Title : Advanced 3D tissue models: Pioneering tools for investigating health and disease
Lucie Bacakova, Institute of Physiology of the Czech Academy of Sciences, Czech Republic
Title : Developing iPSC-derived 3D Outer Blood-Retinal Barrier Disease Models of Choroideremia for Gene Therapy Evaluation
Aradhana Kasimsetty, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), United States